Prof. Dr. Wilfried Weber,

Prof. Dr. Wilfried Weber

Wissenschaftlicher Geschäftsführer
Telefon: +49 (0)681-9300-520
E-Mail: Wilfried.Weber@leibniz-inm.de

Curriculum Vitae

Since 2023      

Scientific Director of INM – Leibniz Institute for New Materials and Professor (W3) for New Materials at Saarland University, Saarbrücken, Germany

2019 – 2023      

Founding Scientific Director of the Cluster of Excellence CIBSS – Centre for Integrative Biological Signalling Studies

2009 – 2023     

Full Professor of Synthetic Biology, Faculty of Biology, University of Freiburg, Germany

2008 – 2009     

Group Leader, Department of Biosystems Science and Engineering, ETH Zurich, Switzerland

2008     

Co-founder of BioVersys GmbH, now BioVersys AG

2006 – 2008    

Group Leader, Institute for Chemical and Bioengineering, ETH Zurich

2003 – 2005  

Postdoc, Institute of Biotechnology, ETH Zurich

2003 – 2005  

Doctoral Studies, Institute of Biotechnology, ETH Zurich with Prof. Martin Fussenegger

2000 

Diplôme d’Ingénieur en Biotechnologie, Ecole Supérieure de Biotechnologie de Strasbourg, Strasbourg, France

Publikationen

2021
Optogenetic approaches for the spatiotemporal control of signal transduction pathways

Kramer, M. M. | Lataster, L. | Weber, Wilfried | Radziwill, G.

International Journal of Molecular Sciences , 2021, 22 (10),
https://dx.doi.org/10.3390/ijms22105300

OPEN ACCESS Weiterlesen
Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors

Hörner, M. | Jerez-Longres, C. | Hudek, A. | Hook, S. | Yousefi, O. S. | Schamel, W. W. A. | Hörner, C. | Zurbriggen, M. D. | Ye, H. | Wagner, H. J. | Weber, Wilfried

Science Advances , 2021, 7 (25),
https://dx.doi.org/10.1126/sciadv.abf0797

OPEN ACCESS Weiterlesen
Green Light-Controlled Gene Switch for Mammalian and Plant Cells

Schneider, N. | Chatelle, C. V. | Ochoa-Fernandez, R. | Zurbriggen, M. D. | Weber, Wilfried

Methods in molecular biology , 2021, 2312 89-107.
https://dx.doi.org/10.1007/978-1-0716-1441-9_6

OPEN ACCESS Weiterlesen
Synthetic Biology: Emerging Concepts to Design and Advance Adeno-Associated Viral Vectors for Gene Therapy

Wagner, H. J. | Weber, Wilfried | Fussenegger, M.

Advanced Science , 2021, 8 (9),
https://dx.doi.org/10.1002/advs.202004018

OPEN ACCESS Weiterlesen
Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice

Schneider, N. | Wieland, F. G. | Kong, D. | Fischer, A. A. M. | Hörner, M. | Timmer, J. | Ye, H. | Weber, Wilfried

Science Advances , 2021, 7 (1),
https://dx.doi.org/10.1126/sciadv.abd3568

OPEN ACCESS Weiterlesen
Cross-TCR antagonism revealed by optogenetically tuning the half-life of the TCR ligand binding

Yousefi, O. S. | Ruggieri, M. | Idstein, V. | von Prillwitz, K. U. | Herr, L. A. | Chalupsky, J. | Köhn, M. | Weber, Wilfried | Timmer, J. | Schamel, W. W. A.

International Journal of Molecular Sciences , 2021, 22 (9),
https://dx.doi.org/10.3390/ijms22094920

OPEN ACCESS Weiterlesen
2020
Human Atrial Fibroblast Adaptation to Heterogeneities in Substrate Stiffness

Emig, R. | Zgierski-Johnston, C. M. | Beyersdorf, F. | Rylski, B. | Ravens, U. | Weber, Wilfried | Kohl, P. | Hörner, M. | Peyronnet, R.

Frontiers in Physiology , 2020, 10
https://dx.doi.org/10.3389/fphys.2019.01526

OPEN ACCESS Weiterlesen
Optogenetic Downregulation of Protein Levels to Control Programmed Cell Death in Mammalian Cells with a Dual Blue-Light Switch

Fischbach, P. | Gonschorek, P. | Baaske, J. | Davies, J. A. | Weber, Wilfried | Zurbriggen, M. D.

Methods in molecular biology , 2020, 2173 159-170.
https://dx.doi.org/10.1007/978-1-0716-0755-8_11

OPEN ACCESS Weiterlesen
Synthesis of a Light-Controlled Phytochrome-Based Extracellular Matrix with Reversibly Adjustable Mechanical Properties

Hörner, M. | Hoess, P. | Emig, R. | Rebmann, B. | Weber, Wilfried

Methods in molecular biology , 2020, 2173 217-231.
https://dx.doi.org/10.1007/978-1-0716-0755-8_15

OPEN ACCESS Weiterlesen
Production, Purification and Characterization of Recombinant Biotinylated Phytochrome B for Extracellular Optogenetics

Hörner, Maximilian | Yousefi, O. Sascha | Schamel, Wolfang W. A. | Weber, Wilfried

Bio-protocol , 2020, 10 (5),
https://en.bio-protocol.org/en/bpdetail?id=3541&type=0

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