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Dr. Busse, Michael 4
Prof. Dr. Wilfried Weber
Wissenschaftlicher Geschäftsführer
Tel.: +49 (0)681-9300-520

Publikationen

Beitrag in referierter Zeitschrift

Urban, NadineHörner, MaximilianWeber, WilfriedDincer, Can. [submitted]OptoAssay - Light-controlleld dynamic bioassay using optogenetic switches. 2024,
Raute, KatrinStrietz, JulianeParigiani, Maria AlejandraAndrieux, GeoffroyThomas, Oliver S.Kistner, Klaus M.Zintchenko, MarinaAichele, PeterHofmann, MaikeZhou, HoujiangWeber, WilfriedBoerries, MelanieSwamy, MahimaMaurer, JochenMinguet, Susana. Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands . Cancer Immunology Research 2023, 11 (6), 810-829.
Molinari, Pamela E.Krapp, Adriana R.Weiner, AndreaBeyer, Hannes M.Kondadi, Arun KumarBlomeier, TimLópez, MelinaBustos-Sanmamed, PilarTevere, EvelynWeber, WilfriedReichert, Andreas S.Calcaterra, Nora B.Beller, MathiasCarrillo, NestorZurbriggen, Matias D.. NERNST: a genetically-encoded ratiometric non-destructive sensing tool to estimate NADP(H) redox status in bacterial, plant and animal systems. Nature Communications 2023, 14 3277.
Su, C.Rodriguez-Franco, M.Lace, B.Nebel, N.Hernandez-Reyes, C.Liang, P.Schulze, E.Mymrikov, E. V.Gross, N. M.Knerr, J.Wang, H.Siukstaite, L.Keller, J.Libourel, C.Fischer, A. A. M.Gabor, K. E.Mark, E.Popp, C.Hunte, C.Weber, WilfriedWendler, P.Stanislas, T.Delaux, P. M.Einsle, O.Grosse, R.Römer, W.Ott, T.. Stabilization of membrane topologies by proteinaceous remorin scaffolds. Nature Communications 2023, 14 (1),
Ates, H. C.Mohsenin, H.Wenzel, C.Glatz, R. T.Wagner, H. J.Bruch, R.Hoefflin, N.Spassov, S.Streicher, L.Lozano-Zahonero, S.Flamm, B.Trittler, R.Hug, M. J.Köhn, M.Schmidt, J.Schumann, S.Urban, G. A.Weber, WilfriedDincer, C.. Biosensor-Enabled Multiplexed On-Site Therapeutic Drug Monitoring of Antibiotics. Advanced Materials 2022, 34 (2),
Johnston, M.Ceren Ates, H.Glatz, R. T.Mohsenin, H.Schmachtenberg, R.Göppert, N.Huzly, D.Urban, G. A.Weber, WilfriedDincer, C.. Multiplexed biosensor for point-of-care COVID-19 monitoring: CRISPR-powered unamplified RNA diagnostics and protein-based therapeutic drug management. Materials Today 2022, 61 129-138.
Thomas, O. S.Rebmann, B.Tonn, M.Schirmeister, I. C.Wehrle, S.Becker, J.Zea Jimenez, G. J.Hook, S.Jäger, S.Klenzendorf, M.Laskowski, M.Kaier, A.Pütz, G.Zurbriggen, M. D.Weber, WilfriedHörner, M.Wagner, H. J.. Reversible Shielding and Immobilization of Liposomes and Viral Vectors by Tailored Antibody-Ligand Interactions. Small 2022, 18 (6), 2105157.
Liu, A. P.Appel, E. A.Ashby, P. D.Baker, B. M.Franco, E.Gu, L.Haynes, K.Joshi, N. S.Kloxin, A. M.Kouwer, P. H. J.Mittal, J.Morsut, L.Noireaux, V.Parekh, S.Schulman, R.Tang, S. K. Y.Valentine, M. T.Vega, S. L.Weber, WilfriedStephanopoulos, N.Chaudhuri, O.. The living interface between synthetic biology and biomaterial design. Nature Materials 2022, 21 (4), 390-397.
Yousefi, O. S.Ruggieri, M.Idstein, V.von Prillwitz, K. U.Herr, L. A.Chalupsky, J.Köhn, M.Weber, WilfriedTimmer, J.Schamel, W. W. A.. Cross-TCR antagonism revealed by optogenetically tuning the half-life of the TCR ligand binding. International Journal of Molecular Sciences 2021, 22 (9),
Hörner, M.Jerez-Longres, C.Hudek, A.Hook, S.Yousefi, O. S.Schamel, W. W. A.Hörner, C.Zurbriggen, M. D.Ye, H.Wagner, H. J.Weber, Wilfried. Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors. Science Advances 2021, 7 (25),
Ochoa-Fernandez, R.Abel, N. B.Wieland, F. G.Schlegel, J.Koch, L. A.Miller, J. B.Engesser, R.Giuriani, G.Brandl, S. M.Timmer, J.Weber, WilfriedOtt, T.Simon, R.Zurbriggen, M. D.. Optogenetic control of gene expression in plants in the presence of ambient white light. Nature Methods 2020, 17 (7), 717-725.
Lienemann, P. S.Vallmajo-Martin, Q.Papageorgiou, P.Blache, U.Metzger, S.Kiveliö, A. S.Milleret, V.Sala, A.Hoehnel, S.Roch, A.Reuten, R.Koch, M.Naveiras, O.Weber, F. E.Weber, WilfriedLutolf, M. P.Ehrbar, M.. Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment. Advanced Science 2020, 7 (7),
Yousefi, O. S.Günther, M.Hörner, M.Chalupsky, J.Wess, M.Brandl, S. M.Smith, R. W.Fleck, C.Kunkel, T.Zurbriggen, M. D.Höfer, T.Weber, WilfriedSchamel, W. W.. Optogenetic control shows that kinetic proofreading regulates the activity of the t cell receptor. eLife 2019, 8
Hörner, M.Raute, K.Hummel, B.Madl, J.Creusen, G.Thomas, O. S.Christen, E. H.Hotz, N.Gübeli, R. J.Engesser, R.Rebmann, B.Lauer, J.Rolauffs, B.Timmer, J.Schamel, W. W. A.Pruszak, J.Römer, W.Zurbriggen, M. D.Friedrich, C.Walther, A.Minguet, S.Sawarkar, R.Weber, Wilfried. Phytochrome-Based Extracellular Matrix with Reversibly Tunable Mechanical Properties. Advanced Materials 2019, 31 (12),
Middleton, A. M.Dal Bosco, C.Chlap, P.Bensch, R.Harz, H.Ren, F.Bergmann, S.Wend, S.Weber, WilfriedHayashi, K. I.Zurbriggen, M. D.Uhl, R.Ronneberger, O.Palme, K.Fleck, C.Dovzhenko, A.. Data-Driven Modeling of Intracellular Auxin Fluxes Indicates a Dominant Role of the ER in Controlling Nuclear Auxin Uptake. Cell Reports 2018, 22 (11), 3044-3057.
Baaske, J.Gonschorek, P.Engesser, R.Dominguez-Monedero, A.Raute, K.Fischbach, P.Müller, K.Cachat, E.Schamel, W. W. A.Minguet, S.Davies, J. A.Timmer, J.Weber, WilfriedZurbriggen, M. D.. Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells. Scientific Reports 2018, 8 (1),
Ketterer, S.Hövermann, D.Guebeli, R. J.Bartels-Burgahn, F.Riewe, D.Altmann, T.Zurbriggen, M. D.Junker, B.Weber, WilfriedMeier, M.. Erratum: Transcription Factor Sensor System for Parallel Quantification of Metabolites On-Chip (Anal. Chem.(2014)86 (12152-12158) DOI: 10.1021/ac503269m). Analytical Chemistry 2015, 87 (15), 8034-8034.
Lienemann, P. S.Devaud, Y. R.Reuten, R.Simona, B. R.Karlsson, M.Weber, WilfriedKoch, M.Lutolf, M. P.Milleret, V.Ehrbar, M.. Locally controlling mesenchymal stem cell morphogenesis by 3D PDGF-BB gradients towards the establishment of an in vitro perivascular niche. Integrative Biology 2015, 7 (1), 101-111.
Agne, M.Blank, I.Emhardt, A. J.Gäbelein, C. G.Gawlas, F.Gillich, N.Gonschorek, P.Juretschke, T. J.Krämer, S. D.Louis, N.Müller, A.Rudorf, A.Schäfer, L. M.Scheidmann, M. C.Schmunk, L. J.Schwenk, P. M.Stammnitz, M. R.Warmer, P. M.Weber, WilfriedFischer, A.Kaufmann, B.Wagner, H. J.Radziwill, G.. Modularized CRISPR/dCas9 effector toolkit for target-specific gene regulation. ACS Synthetic Biology 2014, 3 (12), 986-989.
Ketterer, S.Hövermann, D.Guebeli, R. J.Bartels-Burgahn, F.Riewe, D.Altmann, T.Zurbriggen, M. D.Junker, B.Weber, WilfriedMeier, M.. Transcription factor sensor system for parallel quantification of metabolites on-chip. Analytical Chemistry 2014, 86 (24), 12152-12158.
Müller, K.Engesser, R.Metzger, S.Schulz, S.Kämpf, M. M.Busacker, M.Steinberg, T.Tomakidi, P.Ehrbar, M.Nagy, F.Timmer, J.Zubriggen, M. D.Weber, Wilfried. A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells. Nucleic Acids Research 2013, 41 (7),
Juillot, S.Weber, Wilfried. Biomedicine of synthesis. Biofutur 2013, (339), 27-30.
Gübeli, R. J.Hövermann, D.Seitz, H.Rebmann, B.Schoenmakers, R. G.Ehrbar, M.Charpin-El Hamri, G.Daoud-El Baba, M.Werner, M.Müller, M.Weber, Wilfried. Remote-controlled hydrogel depots for time-scheduled vaccination. Advanced Functional Materials 2013, 23 (43), 5355-5362.
Christen, E. H.Gübeli, R. J.Kaufmann, B.Merkel, L.Schoenmakers, R.Budisa, N.Fussenegger, M.Weber, WilfriedWiltschi, B.. Evaluation of bicinchoninic acid as a ligand for copper(i)-catalyzed azide-alkyne bioconjugations. Organic and Biomolecular Chemistry 2012, 10 (33), 6629-6632.
Haller, C. M.Buerzle, W.Kivelio, A.Perrini, M.Brubaker, C. E.Gubeli, R. J.Mallik, A. S.Weber, WilfriedMessersmith, P. B.Mazza, E.Ochsenbein-Koelble, N.Zimmermann, R.Ehrbar, M.. Mussel-mimetic tissue adhesive for fetal membrane repair: An ex vivo evaluation. Acta Biomaterialia 2012, 8 (12), 4365-4370.
Weber, WilfriedFussenegger, M.. Preface. Methods in Molecular Biology 2012, 813
Kämpf, M. M.Engesser, R.Busacker, M.Hörner, M.Karlsson, M.Zurbriggen, M. D.Fussenegger, M.Timmer, J.Weber, Wilfried. Rewiring and dosing of systems modules as a design approach for synthetic mammalian signaling networks. Molecular BioSystems 2012, 8 (6), 1824-1832.
Christen, E. H.Karlsson, M.Kämpf, M. M.Schoenmakers, R.Gübeli, R. J.Wischhusen, H. M.Friedrich, C.Fussenegger, M.Weber, Wilfried. Conditional DNA-protein interactions confer stimulus-sensing properties to biohybrid materials. Advanced Functional Materials 2011, 21 (15), 2861-2867.
Gitzinger, M.Kemmer, C.El-Baba, M. D.Weber, WilfriedFussenegger, M.. Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin. Proceedings of the National Academy of Sciences of the United States of America 2009, 106 (26), 10638-10643.
Weber, WilfriedSchoenmakers, R.Keller, B.Gitzinger, M.Grau, T.Baba, M. D. E.Sander, P.Fussenegger, M.. A synthetic mammalian gene circuit reveals antituberculosis compounds. Proceedings of the National Academy of Sciences of the United States of America 2008, 105 (29), 9994-9998.
Malphettes, L.Weber, C. C.El-Baba, M. D.Schoenmakers, R. G.Aubel, D.Weber, WilfriedFussenegger, M.. A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1. Nucleic Acids Research 2005, 33 (12), 1-13.
Weber, C. C.Cai, H.Ehrbar, M.Kubota, H.Martiny-Baron, G.Weber, WilfriedDjonov, V.Weber, E.Mallik, A. S.Fussenegger, M.Frei, K.Hubbell, J. A.Zisch, A. H.. Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothelial and vessel organization. Journal of Biological Chemistry 2005, 280 (23), 22445-22453.
Weber, WilfriedMalphettes, L.de Jesus, M.Schoenmakers, R.El-Baba, M. D.Spielmann, M.Keller, B.Weber, C. C.van de Wetering, P.Aubel, D.Wurm, F. M.Fussenegger, M.. Engineered Streptomyces quorum-sensing components enable inducible siRNA-mediated translation control in mammalian cells and adjustable transcription control in mice. Journal of Gene Medicine 2005, 7 (4), 518-525.
Weber, WilfriedMalphettes, L.Rinderknecht, M.Schoenmakers, R. G.Spielmann, M.Keller, B.Van De Wetering, P.Weber, C. C.Fussenegger, M.. Quorum-sensing-based toolbox for regulatable transgene and siRNA expression in mammalian cells. Biotechnology Progress 2005, 21 (1), 178-185.
Fux, C.Langer, D.Kelm, J. M.Weber, WilfriedFussenegger, M.. Erratum: New-generation multicistronic expression platform: pTRIDENT vectors containing size-optimized IRES elements enable homing endonuclease-based cistron swapping into lenitviral expression vectors (Biotechnology and Bioengineering (2004) 86 (174-187)). Biotechnology and Bioengineering 2004, 86 (5), 600.
Fux, C.Langer, D.Kelm, J. M.Weber, WilfriedFussenegger, M.. New-Generation Multicistronic Expression Platform: pTRIDENT Vectors Containing Size-Optimized IRES Elements Enable Homing Endonuclease-Based Cistron Swapping into Lentiviral Expression Vectors. Biotechnology and Bioengineering 2004, 86 (2), 174-187.
Cellesi, F.Weber, WilfriedFussenegger, M.Hubbell, J. A.Tirelli, N.. Towards a fully synthetic substitute of alginate: Optimization of a thermal gelation/chemical cross-linking scheme ("tandem" gelation) for the production of beads and liquid-core capsules. Biotechnology and Bioengineering 2004, 88 (6), 740-749.
Weber, WilfriedMarty, R. R.Link, N.Ehrbar, M.Keller, B.Weber, C. C.Zisch, A. H.Heinzen, C.Djonov, V.Fussenegger, M.. Conditional human VEGF-mediated vascularization in chicken embryos using a novel temperature-inducible gene regulation (TIGR) system. Nucleic acids research 2003, 31 (12),
Fux, C.Weber, WilfriedDaoud-El Baba, M.Heinzen, C.Aubel, D.Fussenegger, M.. Novel macrolide-adjustable bidirectional expression modules for coordinated expression of two different transgenes in mice. Journal of Gene Medicine 2003, 5 (12), 1067-1079.
Weber, WilfriedSchoenmakers, R.Spielmann, M.El-Baba, M. D.Folcher, M.Keller, B.Weber, C. C.Link, N.van de Wetering, P.Heinzen, C.Jolivet, B.Séquin, U.Aubel, D.Thompson, C. J.Fussenegger, M.. Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice. Nucleic acids research 2003, 31 (14),

Beitrag in Tagungsband

Ceren Ates, H.Schneider, N.Bruch, R.Weber, WilfriedUrban, G.Dincer, C.. Antibody-free assay for electrochemical ß-lactam monitoring. In: 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 , October 27-31, 2019, Basel . CBMS; 2019: 1696-1697.
Bruch, R.Baaske, J.Chatelle, C.Weber, WilfriedUrban, G. A.Dincer, C.. Microrna diagnostics on an electrochemical biosensor via CRISPR/CAS13A technology. In: 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, October 27-31, 2019, Basel . CBMS; 2019: 65-66.
Hömer, M.Hotz, N.Kaufmann, B.Gübeli, R.Christen, E.Büning, H.Grimm, D.Zurbriggen, M. D.Weber, Wilfried. Engineering light- and pharmacologically triggered extracellular biological switches. In: Synthetic Biology: Engineering, Evolution, and Design Conference 2015, SEED 2015, June 10-13, 2015, Boston . AIChE; 2015: 807.

Beitrag in Buch

Rebmann, B.van Hoogevest, P.Matias, Z.Weber, Wilfried. Pharmaceutical aspects of biologics from animal cell culture processes: Spatiotemporally controlled delivery of biopharmaceuticals. In:Hauser, Hans-Jörg, eds. Animal Cell Biotechnology: In Biologics Production. Springer; 2014: 649-692

Vortrag (eingeladen)

Weber, Wilfried. Antibodies - from bench to bedside. Vorlesung, November 1, 2023, ETH Zürich , Basel
Weber, Wilfried. Biobased and Living Materials. Strategieseminar des DWI - Leibniz-Institut für Interaktive Materialien e.V. Aachen, June 13 2023, Abdij Rolduc Kerkrade
Weber, Wilfried. Directed Evolution of Materials. Forum Experiment! 2023, May 23-24, 2023, Volkswagen-Stiftung, Xplanatorium Hannover
Weber, Wilfried. Lebende Materialien. Absolventenfeier MWWT, May 26, 2023, Universität des Saarlandes, Saarbrücken
Weber, Wilfried. Lebende Materialien - ein neues Paradigma in den Materialwissenschaften. Wissenschaftsforum des MINT-Campus, July 11, 2023, Alte Schmelz St. Ingbert
Weber, Wilfried. Making New Materials with Synthetic Biology. Vorlesung, November 8, 2023, ETH Zürich, Basel
Weber, Wilfried. Molecular Optogenetics - Programmich Cells with Light. ATTACK Symposium, October 24, 2023, Freinsheim
Weber, Wilfried. Molecular Optogenetics - Programming Cells and Biomaterials with Light. Maxime Dahan Symposium, December 15, 2023, Institut Curie Research Center Paris
Weber, Wilfried. Molecular Optogenetics - Programming Cells and Materials with Light. Young Invesitgator Symposium, April 21, 2023, Universitätsklinikum des Saarlandes, Homburg Saar
Weber, Wilfried. Molecular Optogenetics - Programming Cells and Materials with Light. Syn-Bio Meeting, September 12, 2023, Ben-Gurion University of the Negev, Beer-Sheva
Weber, Wilfried. Programming Cells and Materials with Light. Optogenetics Meeting 2023, October 4, 2023, Universität Göttingen, Landhotel am Rotehberg, Volpreishausen
Weber, Wilfried. Programming Cells and Materials with Synthetic Biology. Fakultäts-Symposium, November 15, 2023, Universität des Saarlandes, Saarbrücken
Weber, Wilfried. Programming Materials with Synthetic Biology. International Synthetic Biology Workshop, March 22, 2023, Technische Universität Darmstadt
Weber, Wilfried. Programming materials with synthetic biology. German Association of Synthetic Biology (GASB) Conference, September 18, 2023, Freiburg i.Br.
Weber, Wilfried. Programmng Cells to Assemble New Materials from Waste- and Byproducts. Sitzung Themennetzwerk Materialwissenschaften und Werkstofftechnik der acatech, October 9, 2023, BAM Berlin Adlershof
Weber, Wilfried. Synthetic biology-inspired deisgn of materials. Kolloquium der Fachrichtung Materialwissenschaft und Werkstofftechnik, May 09, 2023, Universität des Saarlandes Saarbrücken
Weber, Wilfried. Synthetic Biology-inspired design of advanced materials. Summer School Ryon Rhein-Main-Universities, September 4, 2023, Merck Innovation Center, Darmstadt

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