Prof. Dr. Wilfried Weber,

Prof. Dr. Wilfried Weber

Scientific Director
Phone: +49 (0)681-9300-520

Curriculum Vitae

Since 2023      

Scientific Director of INM – Leibniz Institute for New Materials and Professor (W3) for New Materials at Saarland University, Saarbrücken, Germany


2019 – 2023      

Founding Scientific Director of the Cluster of Excellence CIBSS – Centre for Integrative Biological Signalling Studies


2009 – 2023     

Full Professor of Synthetic Biology, Faculty of Biology, University of Freiburg, Germany


2008 – 2009     

Group Leader, Department of Biosystems Science and Engineering, ETH Zurich, Switzerland


2008     

Co-founder of BioVersys GmbH, now BioVersys AG


2006 – 2008    

Group Leader, Institute for Chemical and Bioengineering, ETH Zurich


2003 – 2005  

Postdoc, Institute of Biotechnology, ETH Zurich


2003 – 2005  

Doctoral Studies, Institute of Biotechnology, ETH Zurich with Prof. Martin Fussenegger


2000 

Diplôme d’Ingénieur en Biotechnologie, Ecole Supérieure de Biotechnologie de Strasbourg, Strasbourg, France


Publications

2019
Biofunctionalized Materials Featuring Feedforward and Feedback Circuits Exemplified by the Detection of Botulinum Toxin A

Wagner, H. J. | Kemmer, S. | Engesser, R. | Timmer, J. | Weber, Wilfried

Advanced Science , 2019, 6 (4), 1801320.
https://dx.doi.org/10.1002/advs.201801320

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Design of a human rhinovirus-14 3C protease-inducible caspase-3

Wagner, H. J. | Weber, Wilfried

Molecules , 2019, 24 (10),
https://dx.doi.org/10.3390/molecules24101945

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Optogenetic control shows that kinetic proofreading regulates the activity of the t cell receptor

Yousefi, O. S. | Günther, M. | Hörner, M. | Chalupsky, J. | Wess, M. | Brandl, S. M. | Smith, R. W. | Fleck, C. | Kunkel, T. | Zurbriggen, M. D. | Höfer, T. | Weber, Wilfried | Schamel, W. W.

eLife , 2019, 8
https://dx.doi.org/10.7554/eLife.42475

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2018
Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells

Baaske, J. | Gonschorek, P. | Engesser, R. | Dominguez-Monedero, A. | Raute, K. | Fischbach, P. | Müller, K. | Cachat, E. | Schamel, W. W. A. | Minguet, S. | Davies, J. A. | Timmer, J. | Weber, Wilfried | Zurbriggen, M. D.

Scientific Reports , 2018, 8 (1),
https://dx.doi.org/10.1038/s41598-018-32929-7

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Synthetic Biology Makes Polymer Materials Count

Beyer, H. M. | Engesser, R. | Hörner, M. | Koschmieder, J. | Beyer, P. | Timmer, J. | Zurbriggen, M. D. | Weber, Wilfried

Advanced Materials , 2018, 30 (21),
https://dx.doi.org/10.1002/adma.201800472

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Generic and reversible opto-trapping of biomolecules

Beyer, H. M. | Thomas, O. S. | Riegel, N. | Zurbriggen, M. D. | Weber, Wilfried | Hörner, M.

Acta Biomaterialia , 2018, 79 276-282.
https://dx.doi.org/10.1016/j.actbio.2018.08.032

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A Green-Light-Responsive System for the Control of Transgene Expression in Mammalian and Plant Cells

Chatelle, C. | Ochoa-Fernandez, R. | Engesser, R. | Schneider, N. | Beyer, H. M. | Jones, A. R. | Timmer, J. | Zurbriggen, M. D. | Weber, Wilfried

ACS Synthetic Biology , 2018, 7 (5), 1349-1358.
https://www.dx.doi.org/10.1021/acssynbio.7b00450

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Optogenetic control of focal adhesion kinase signaling

Hörner, M. | Chatelle, C. | Mühlhäuser, W. W. D. | Stocker, D. R. | Coats, M. | Weber, Wilfried | Radziwill, G.

Cellular Signalling , 2018, 42 176-183.
https://dx.doi.org/10.1016/j.cellsig.2017.10.012

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OptoBase: A Web Platform for Molecular Optogenetics

Kolar, K. | Knobloch, C. | Stork, H. | Žnidarič, M. | Weber, Wilfried

ACS Synthetic Biology , 2018, 7 (7), 1825-1828.
https://www.dx.doi.org/10.1021/acssynbio.8b00120

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Data-Driven Modeling of Intracellular Auxin Fluxes Indicates a Dominant Role of the ER in Controlling Nuclear Auxin Uptake

Middleton, A. M. | Dal Bosco, C. | Chlap, P. | Bensch, R. | Harz, H. | Ren, F. | Bergmann, S. | Wend, S. | Weber, Wilfried | Hayashi, K. I. | Zurbriggen, M. D. | Uhl, R. | Ronneberger, O. | Palme, K. | Fleck, C. | Dovzhenko, A.

Cell Reports , 2018, 22 (11), 3044-3057.
https://dx.doi.org/10.1016/j.celrep.2018.02.074

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