Prof. Dr. Wilfried Weber,

Prof. Dr. Wilfried Weber

Scientific Director
Phone: +49 (0)681-9300-520

Curriculum Vitae

Since 2023      

Scientific Director of INM – Leibniz Institute for New Materials and Professor (W3) for New Materials at Saarland University, Saarbrücken, Germany


2019 – 2023      

Founding Scientific Director of the Cluster of Excellence CIBSS – Centre for Integrative Biological Signalling Studies


2009 – 2023     

Full Professor of Synthetic Biology, Faculty of Biology, University of Freiburg, Germany


2008 – 2009     

Group Leader, Department of Biosystems Science and Engineering, ETH Zurich, Switzerland


2008     

Co-founder of BioVersys GmbH, now BioVersys AG


2006 – 2008    

Group Leader, Institute for Chemical and Bioengineering, ETH Zurich


2003 – 2005  

Postdoc, Institute of Biotechnology, ETH Zurich


2003 – 2005  

Doctoral Studies, Institute of Biotechnology, ETH Zurich with Prof. Martin Fussenegger


2000 

Diplôme d’Ingénieur en Biotechnologie, Ecole Supérieure de Biotechnologie de Strasbourg, Strasbourg, France


Publications

2021
Cross-TCR antagonism revealed by optogenetically tuning the half-life of the TCR ligand binding

Yousefi, O. S. | Ruggieri, M. | Idstein, V. | von Prillwitz, K. U. | Herr, L. A. | Chalupsky, J. | Köhn, M. | Weber, Wilfried | Timmer, J. | Schamel, W. W. A.

International Journal of Molecular Sciences , 2021, 22 (9),
https://dx.doi.org/10.3390/ijms22094920

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2020
Human Atrial Fibroblast Adaptation to Heterogeneities in Substrate Stiffness

Emig, R. | Zgierski-Johnston, C. M. | Beyersdorf, F. | Rylski, B. | Ravens, U. | Weber, Wilfried | Kohl, P. | Hörner, M. | Peyronnet, R.

Frontiers in Physiology , 2020, 10
https://dx.doi.org/10.3389/fphys.2019.01526

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Optogenetic Downregulation of Protein Levels to Control Programmed Cell Death in Mammalian Cells with a Dual Blue-Light Switch

Fischbach, P. | Gonschorek, P. | Baaske, J. | Davies, J. A. | Weber, Wilfried | Zurbriggen, M. D.

Methods in molecular biology , 2020, 2173 159-170.
https://dx.doi.org/10.1007/978-1-0716-0755-8_11

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Synthesis of a Light-Controlled Phytochrome-Based Extracellular Matrix with Reversibly Adjustable Mechanical Properties

Hörner, M. | Hoess, P. | Emig, R. | Rebmann, B. | Weber, Wilfried

Methods in molecular biology , 2020, 2173 217-231.
https://dx.doi.org/10.1007/978-1-0716-0755-8_15

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Production, Purification and Characterization of Recombinant Biotinylated Phytochrome B for Extracellular Optogenetics

Hörner, Maximilian | Yousefi, O. Sascha | Schamel, Wolfang W. A. | Weber, Wilfried

Bio-protocol , 2020, 10 (5),
https://en.bio-protocol.org/en/bpdetail?id=3541&type=0

Multichromatic Control of Signaling Pathways in Mammalian Cells

Kramer, M. M. | Mühlhäuser, W. W. D. | Weber, Wilfried | Radziwill, G.

Advanced Biosystems , 2020,
https://dx.doi.org/10.1002/adbi.202000196

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Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment

Lienemann, P. S. | Vallmajo-Martin, Q. | Papageorgiou, P. | Blache, U. | Metzger, S. | Kiveliö, A. S. | Milleret, V. | Sala, A. | Hoehnel, S. | Roch, A. | Reuten, R. | Koch, M. | Naveiras, O. | Weber, F. E. | Weber, Wilfried | Lutolf, M. P. | Ehrbar, M.

Advanced Science , 2020, 7 (7),
https://dx.doi.org/10.1002/advs.201903395

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Flow-based regenerable chemiluminescence receptor assay for the detection of tetracyclines

Meyer, V. K. | Chatelle, C. V. | Weber, Wilfried | Niessner, R. | Seidel, M.

Analytical and Bioanalytical Chemistry , 2020, 412 (14), 3467-3476.
https://dx.doi.org/10.1007/s00216-019-02368-y

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Optogenetic control of gene expression in plants in the presence of ambient white light

Ochoa-Fernandez, R. | Abel, N. B. | Wieland, F. G. | Schlegel, J. | Koch, L. A. | Miller, J. B. | Engesser, R. | Giuriani, G. | Brandl, S. M. | Timmer, J. | Weber, Wilfried | Ott, T. | Simon, R. | Zurbriggen, M. D.

Nature Methods , 2020, 17 (7), 717-725.
https://dx.doi.org/10.1038/s41592-020-0868-y

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A graphical user interface to design high-throughput optogenetic experiments with the optoPlate-96

Thomas, O. S. | Hörner, M. | Weber, Wilfried

Nature Protocols , 2020, 15 (9), 2785-2787.
https://dx.doi.org/10.1038/s41596-020-0349-x

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