Dynamic Biomaterials

Prof. Dr. Aránzazu del Campo
Prof. Dr. Aránzazu del Campo
Head of Dynamic Biomaterials
Telefon: +49 (0)681-9300-510

Contact

Dr. Aleeza Farrukh
Stv. Leiterin Dynamische Biomaterialien
Phone: +49 (0)681-9300-315
Martina Bonnard
Secretary
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Research

Hydrogels with latent properties

By integrating phototriggers and light-responsive molecular motors in polymeric networks, we develop 4D hydrogels with optoregulated (bio)chemical activity, crosslinking, degradation, or mechanoactuation. These are used for biophysical studies of cell response to changes in the biochemical and mechanical signals of the extracellular environment.

Model Cellular Microenvironments

We build synthetic models of cell-matrix and cell-cell interfaces with encoded biochemical, mechanical and dimensional signals. To accelerate discovery, we develop material microarrays for high-throughput biophysical experimentation and apply them to study multifactorial cell responses.

Living Therapeutic Devices

We develop bioinks and apply biofabrication technologies for functional and safe encapsulation of cells in medical devices. We focus on self-replenishable living therapeutic materials which integrate drug biofactories and have unlimited therapeutic release. We aim for innovation in ocular therapeutics with living, self-replenishable drug-eluting contact lenses.

Partner

Selected Publications

2016
Stick-slip friction of PDMS surfaces for bioinspired adhesives

Xue, Longjian | Pham, Jonathan T. | Iturri, Jagoba | del Campo, Aránzazu

Langmuir , 2016, 32 (10), 2428-2435.
http://dx.doi.org/10.1021/acs.langmuir.6b00513

Al2O3micro- and nanostructures affect vascular cell response

Kiefer, Karin | Akp | Haidar, Ayman | Ikier, Tuba | Akkan, Ca | Akman, Erhan | Lee, Juseok | Martinez Miró, Marina | Kaçar, Elif | Demir, Arif | Veith, Michael | Ural, Dilek | Kasap, Murat | Kesmez, Mehmet | Abdul-Khaliq, Hashim | Aktas, Oral C.

RSC Advances , 2016, 6 (21), 17460-17469.
http://dx.doi.org/10.1039/C5RA21775J

Surface modification by plasma etching impairs early vascularization and tissue incorporation of porous polyethylene (Medpor®) implants

Laschke, Matthias W. | Augustin, Victor A. | Sahin, Fadime | Anschütz, Dieter | Metzger, Wolfgang | Scheuer, Claudia | Bischoff, Markus | Aktas, Oral C. | Menger, Michael D.

Journal of Biomedical Materials Research Part B: Applied Biomaterials , 2016, 104 (8), 1738-1748.
http://dx.doi.org/10.1002/jbm.b.33528

2015
Gauging and tuning cross-linking kinetics of catechol-PEG adhesives via catecholamine functionalization

Paez, Julieta I. | Ustahüseyin, Oya | Serrano, Cristina | Ton, Xuan-Anh | Shafiq, Zahid | Auernhammer, Günter K. | d’Ischia, Marco | del Campo, Aránzazu

Biomacromolecules , 2015, 16 (12), 3811-3818.
http://dx.doi.org/10.1021/acs.biomac.5b01126

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