Dynamic Biomaterials

Prof. Dr. Aránzazu del Campo
Prof. Dr. Aránzazu del Campo
Head of Dynamic Biomaterials
Telefon: +49 (0)681-9300-510
E-mail: Aranzazu.DelCampo@leibniz-inm.de
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Contact

Dr. Aleeza Farrukh, INM – Leibniz-Institut für Neue Materialien gGmbH
Dr. Aleeza Farrukh
Stv. Leiterin Dynamische Biomaterialien
Phone: +49 (0)681-9300-315
E-mail: aleeza.farrukh@leibniz-inm.de
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Martina Bonnard
Secretary
Phone: +49 (0)681-9300-397
E-mail: martina.bonnard@leibniz-inm.de
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Team Members
B.Sc. Israa Abdulrahman Mohammed Kheir Elh
Phone: +49 (0)681-9300-351
E-mail: Israa.Abdulrahman@leibniz-inm.de
Daniel Ablahad
Phone: +49 (0)681-9300-181
E-mail: Daniel.Ablahad@leibniz-inm.de
Britta Abt
Phone: +49 (0)681-9300-363
E-mail: Britta.Abt@leibniz-inm.de
Dr.-Ing. Sener Albayrak
Phone: +49 (0)681-9300-157
E-mail: Sener.Albayrak@leibniz-inm.de
Dr. Gerardo Asensio Martín
Phone: +49 (0)681-9300-315
E-mail: gerardo.asensiomartin@leibniz-inm.de
Dipl.-Chem. Stefan Brück
Phone: +49 (0)681-9300-245
E-mail: stefan.brueck@leibniz-inm.de
B.Sc. Jesús Chong Talavera
Phone: +49 (0)681-9300-108/251
E-mail: jesus.chong@leibniz-inm.de
Semhar Eyob
Phone: +49 (0)681-9300-414
E-mail: semhar.eyob@leibniz-inm.de
M.Sc. Hafiz Syed Usama bin Farrukh
Phone: +49 (0)681-9300-360
E-mail: Usama.Farrukh@leibniz-inm.de
Dr. Aleeza Farrukh
Phone: +49 (0)681-9300-315
E-mail: aleeza.farrukh@leibniz-inm.de
ORCID: https://orcid.org/0000-0002-0711-0419
Dr. Jun Feng
Phone: +49 (0)681-9300-214
E-mail: jun.feng@leibniz-inm.de
M.Sc. Annalena Elisabeth Frank
E-mail: annalena.frank@leibniz-inm.de
B.Sc. Daniel Alfonso Garcia Sanchez
Phone: +49 (0)681-9300-245
E-mail: daniel.sanchez@leibniz-inm.de
Dr. Hannah Jahn-Kelleter
Phone: +49 (0)681-9300-384
E-mail: Hannah.Jahn-Kelleter@leibniz-inm.de
M.Sc. Zahra Kafrashian
Phone: +49 (0)681-9300-237
E-mail: zahra.kafrashian@leibniz-inm.de
ORCID: https://orcid.org/0000-0003-2960-7597
M.Sc. Hanuman Chowdary Kalari
Phone: +49 (0)681-9300-401
E-mail: Hanuman.Kalari@leibniz-inm.de
ORCID: https://orcid.org/0000-0002-2229-317X
Dr. Jennifer Yvonne Kasper
Phone: +49 (0)681-9300-345
E-mail: Jennifer.Kasper@leibniz-inm.de
M.Sc. Mokhamad Khamdan
Phone: +49 (0)681-9300-349
E-mail: mokhamad.khamdan@leibniz-inm.de
Dr. Steffen Krauser
Phone: +49 (0)681-9300-401
E-mail: steffen.krauser@leibniz-inm.de
Dr. Rinku Kumar
Phone: +49 (0)681-9300-316
E-mail: rinku.kumar@leibniz-inm.de
Prof. Dr. Juan Mancebo Aracil
Phone: +49 (0)681-9300-155
E-mail: juan.mancebo@leibniz-inm.de
M.Sc. Joëlle Aurelie Mekontso Ngaffo
Phone: +49 (0)681-9300-247
E-mail: joelle.mekontso@leibniz-inm.de
Dr. Christian Müller
Phone: +49 (0)681-9300-315
E-mail: christian.mueller@leibniz-inm.de
M.Sc. Ann-Cathrin Schlapp
Phone: +49 (0)681-9300-214
E-mail: Ann-Cathrin.Schlapp@leibniz-inm.de
Silke Siegrist
Phone: +49 (0)681-9300-363
E-mail: silke.siegrist@leibniz-inm.de
M.Sc. Therese Steudter
Phone: +49 (0)681-9300-384
E-mail: therese.steudter@leibniz-inm.de
M.Sc. Lara Luana Teruel Enrico
Phone: +49 (0)681-9300-282
E-mail: LaraLuana.TeruelEnrico@leibniz-inm.de
Lennart Weismantel
Phone: +49 (0)681-9300-152
E-mail: lennart.weismantel@leibniz-inm.de
Research

Hydrogels with latent properties

By integrating phototriggers and light-responsive molecular motors in polymeric networks, we develop 4D hydrogels with optoregulated (bio)chemical activity, crosslinking, degradation, or mechanoactuation. These are used for biophysical studies of cell response to changes in the biochemical and mechanical signals of the extracellular environment.

Model Cellular Microenvironments

We build synthetic models of cell-matrix and cell-cell interfaces with encoded biochemical, mechanical and dimensional signals. To accelerate discovery, we develop material microarrays for high-throughput biophysical experimentation and apply them to study multifactorial cell responses.

Living Therapeutic Devices

We develop bioinks and apply biofabrication technologies for functional and safe encapsulation of cells in medical devices. We focus on self-replenishable living therapeutic materials which integrate drug biofactories and have unlimited therapeutic release. We aim for innovation in ocular therapeutics with living, self-replenishable drug-eluting contact lenses.

Partner

Selected Publications

2019
Optoregulated Drug Release from an Engineered Living Material: Self-Replenishing Drug Depots for Long-Term, Light-Regulated Delivery

Sankaran, Shrikrishnan | Becker, Judith | Wittmann, Christoph | del Campo, Aránzazu

Small , 2019, 15 1804717/1-6.
https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.201804717

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Optoregulated Protein Release from an Engineered Living Material

Sankaran, Shrikrishnan | del Campo, Aránzazu

Advanced Biosystems , 2019, 3 (2), 1800312/1-7.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adbi.201800312

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2018
Human Co- and Triple-Culture Model of the Alveolar-Capillary Barrier on a Basement Membrane Mimic

Dohle, Eva | Singh, Smriti | Nishigushi, Akihiro | Fischer, Thorsten | Wessling, Matthias | Möller, Martin | Sader, Robert | Kasper, Jennifer Y. | Ghanaati, Shahram | Kirkpatrick, C. James

Tissue Engineering Part C: Methods , 2018, 24 (9), 495-503.
https://www.liebertpub.com/doi/abs/10.1089/ten.tec.2018.0087

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Photoactivatable Adhesive Ligands for Light-Guided Neuronal Growth

Farrukh, Aleeza | Fan, Wenqiang | Zhao, Shifang | Salierno, Marcelo | Paez, Julieta I. | Del Campo, Aranzazu

ChemBioChem , 2018, 19 (12), 1271-1279.
https://onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201800118

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Microenvironments Designed to Support Growth and Function of Neuronal Cells

Farrukh, Aleeza | Zhao, Shifang | del Campo, Aránzazu

Frontiers in Materials , 2018, 5 (62),
https://www.frontiersin.org/article/10.3389/fmats.2018.00062

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In Situ, Light-Guided Axon Growth on Biomaterials via Photoactivatable Laminin Peptidomimetic IK(HANBP)VAV

Farrukh, Aleeza | Zhao, Shifang | Paez, Julieta I. | Kavyanifar, Atria | Salierno, Marcelo | Cavalié, Adolfo | del Campo, Aránzazu

ACS Applied Materials & Interfaces , 2018, 10 (48), 41129-41137.
https://doi.org/10.1021/acsami.8b15517

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Active superelasticity in three-dimensional epithelia of controlled shape

Latorre, Ernest | Kale, Sohan | Casares, Laura | Gómez-González, Manuel | Uroz, Marina | Valon, Léo | Nair, Roshna V. | Garreta, Elena | Montserrat, Nuria | del Campo, Aránzazu | Ladoux, Benoit | Arroyo, Marino | Trepat, Xavier

Nature , 2018, 563 (7730), 203-208.
https://doi.org/10.1038/s41586-018-0671-4

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A Photoactivatable α5β1-Specific Integrin Ligand

Nair, Roshna V. | Farrukh, Aleeza | del Campo, Aránzazu

ChemBioChem , 2018, 19 (12), 1280-1287.
https://onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201800180

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A bio-based route to the carbon-5 chemical glutaric acid and to bionylon-6,5 using metabolically engineered Corynebacterium glutamicum

Rohles, Christina Maria | Gläser, Lars | Kohlstedt, Michael | Gießelmann, Gideon | Pearson, Samuel | del Campo, Aránzazu | Becker, Judith | Wittmann, Christoph

Green Chemistry , 2018, 20 (20), 4662-4674.
http://dx.doi.org/10.1039/C8GC01901K

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Toward Light-Regulated Living Biomaterials

Sankaran, Shrikrishnan | Zhao, Shifang | Muth, Christina | Paez, Julieta | del Campo, Aránzazu

Advanced Science , 2018, 5 (8), 1800383.
https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.201800383

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