Dynamic Biomaterials

Prof. Dr. Aránzazu del Campo
Prof. Dr. Aránzazu del Campo
Head of Dynamic Biomaterials
Telefon: +49 (0)681-9300-510
E-mail: Aranzazu.DelCampo@leibniz-inm.de
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Contact

Dr. Aleeza Farrukh, INM – Leibniz-Institut für Neue Materialien gGmbH
Dr. Aleeza Farrukh
Stv. Leiterin Dynamische Biomaterialien
Phone: +49 (0)681-9300-315
E-mail: aleeza.farrukh@leibniz-inm.de
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Martina Bonnard
Secretary
Phone: +49 (0)681-9300-397
E-mail: martina.bonnard@leibniz-inm.de
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Team Members
B.Sc. Israa Abdulrahman Mohammed Kheir Elh
Phone: +49 (0)681-9300-351
E-mail: Israa.Abdulrahman@leibniz-inm.de
Daniel Ablahad
Phone: +49 (0)681-9300-181
E-mail: Daniel.Ablahad@leibniz-inm.de
Britta Abt
Phone: +49 (0)681-9300-363
E-mail: Britta.Abt@leibniz-inm.de
Dr.-Ing. Sener Albayrak
Phone: +49 (0)681-9300-157
E-mail: Sener.Albayrak@leibniz-inm.de
Dr. Gerardo Asensio Martín
Phone: +49 (0)681-9300-315
E-mail: gerardo.asensiomartin@leibniz-inm.de
Dipl.-Chem. Stefan Brück
Phone: +49 (0)681-9300-245
E-mail: stefan.brueck@leibniz-inm.de
B.Sc. Jesús Chong Talavera
Phone: +49 (0)681-9300-108/251
E-mail: jesus.chong@leibniz-inm.de
Semhar Eyob
Phone: +49 (0)681-9300-414
E-mail: semhar.eyob@leibniz-inm.de
M.Sc. Hafiz Syed Usama bin Farrukh
Phone: +49 (0)681-9300-360
E-mail: Usama.Farrukh@leibniz-inm.de
Dr. Aleeza Farrukh
Phone: +49 (0)681-9300-315
E-mail: aleeza.farrukh@leibniz-inm.de
ORCID: https://orcid.org/0000-0002-0711-0419
Dr. Jun Feng
Phone: +49 (0)681-9300-214
E-mail: jun.feng@leibniz-inm.de
M.Sc. Annalena Elisabeth Frank
E-mail: annalena.frank@leibniz-inm.de
B.Sc. Daniel Alfonso Garcia Sanchez
Phone: +49 (0)681-9300-245
E-mail: daniel.sanchez@leibniz-inm.de
Dr. Hannah Jahn-Kelleter
Phone: +49 (0)681-9300-384
E-mail: Hannah.Jahn-Kelleter@leibniz-inm.de
M.Sc. Zahra Kafrashian
Phone: +49 (0)681-9300-237
E-mail: zahra.kafrashian@leibniz-inm.de
ORCID: https://orcid.org/0000-0003-2960-7597
M.Sc. Hanuman Chowdary Kalari
Phone: +49 (0)681-9300-401
E-mail: Hanuman.Kalari@leibniz-inm.de
ORCID: https://orcid.org/0000-0002-2229-317X
Dr. Jennifer Yvonne Kasper
Phone: +49 (0)681-9300-345
E-mail: Jennifer.Kasper@leibniz-inm.de
M.Sc. Mokhamad Khamdan
Phone: +49 (0)681-9300-349
E-mail: mokhamad.khamdan@leibniz-inm.de
Dr. Steffen Krauser
Phone: +49 (0)681-9300-401
E-mail: steffen.krauser@leibniz-inm.de
Dr. Rinku Kumar
Phone: +49 (0)681-9300-316
E-mail: rinku.kumar@leibniz-inm.de
Prof. Dr. Juan Mancebo Aracil
Phone: +49 (0)681-9300-155
E-mail: juan.mancebo@leibniz-inm.de
M.Sc. Joëlle Aurelie Mekontso Ngaffo
Phone: +49 (0)681-9300-247
E-mail: joelle.mekontso@leibniz-inm.de
Dr. Christian Müller
Phone: +49 (0)681-9300-315
E-mail: christian.mueller@leibniz-inm.de
M.Sc. Ann-Cathrin Schlapp
Phone: +49 (0)681-9300-214
E-mail: Ann-Cathrin.Schlapp@leibniz-inm.de
Silke Siegrist
Phone: +49 (0)681-9300-363
E-mail: silke.siegrist@leibniz-inm.de
M.Sc. Therese Steudter
Phone: +49 (0)681-9300-384
E-mail: therese.steudter@leibniz-inm.de
M.Sc. Lara Luana Teruel Enrico
Phone: +49 (0)681-9300-282
E-mail: LaraLuana.TeruelEnrico@leibniz-inm.de
Lennart Weismantel
Phone: +49 (0)681-9300-152
E-mail: lennart.weismantel@leibniz-inm.de
Research

Hydrogels with latent properties

By integrating phototriggers and light-responsive molecular motors in polymeric networks, we develop 4D hydrogels with optoregulated (bio)chemical activity, crosslinking, degradation, or mechanoactuation. These are used for biophysical studies of cell response to changes in the biochemical and mechanical signals of the extracellular environment.

Model Cellular Microenvironments

We build synthetic models of cell-matrix and cell-cell interfaces with encoded biochemical, mechanical and dimensional signals. To accelerate discovery, we develop material microarrays for high-throughput biophysical experimentation and apply them to study multifactorial cell responses.

Living Therapeutic Devices

We develop bioinks and apply biofabrication technologies for functional and safe encapsulation of cells in medical devices. We focus on self-replenishable living therapeutic materials which integrate drug biofactories and have unlimited therapeutic release. We aim for innovation in ocular therapeutics with living, self-replenishable drug-eluting contact lenses.

Partner

Selected Publications

2020
Near-infrared-light regulated angiogenesis in a 4D hydrogel

Zheng, Yijun | Chen, Zhijun | Jiang, Qiyang | Feng, Jun | Wu, Si | del Campo, Aránzazu

Nanoscale , 2020, 12 (25), 13654-13661.
http://dx.doi.org/10.1039/D0NR02552F

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4D hydrogel for dynamic cell culture with orthogonal, wavelength-dependent mechanical and biochemical cues

Zheng, Yijun | Liong Han, Mitchell Kim | Jiang, Qiyang | Li, Bin | Feng, Jun | del Campo, Aránzazu

Materials Horizons , 2020, 7 111-120.
http://dx.doi.org/10.1039/C9MH00665F

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Thiol-Methylsulfone-Based Hydrogels for 3D Cell Encapsulation

Paez, Julieta I. | Farrukh, Aleeza | Valbuena Mendoza, Rocío | Włodarczyk-Biegun, Małgorzata K. | del Campo, Aránzazu

ACS Applied Materials & Interfaces , 2020, 12 (7), 8062-8072.
https://doi.org/10.1021/acsami.0c00709

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Supramolecular block copolymers as novel UV and NIR responsive nanocarriers based on a photolabile coumarin unit

Roche, Alejandro | Terriac, Emmanuel | Tejedor, Rosa M. | Oriol, Luis | del Campo, Aránzazu | Piñol, Milagros

European Polymer Journal , 2020, 126 109561.
http://www.sciencedirect.com/science/article/pii/S0014305719320750

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2019
The mechanics of single cross-links which mediate cell attachment at a hydrogel surface

Çolak, Arzu | Li, Bin | Blass, Johanna | Koynov, Kaloian | del Campo, Aranzazu | Bennewitz, Roland

Nanoscale , 2019, 11 (24), 11596–11604.
http://dx.doi.org/10.1039/C9NR01784D

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Goosebumps-Inspired Microgel Patterns with Switchable Adhesion and Friction

Li, Bin | Kappl, Michael | Han, Lu | Cui, Jiaxi | Zhou, Feng | del Campo, Aránzazu

Small , 2019, 15 (35), 1902376.
https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.201902376

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4D Biomaterials for Light-Guided Angiogenesis

Farrukh, Aleeza | Paez, Julieta I. | del Campo, Aránzazu

Advanced Functional Materials , 2019, 29 1807734/1-11.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201807734

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Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration

Hetmanski, Joseph H. R. | de Belly, Henry | Busnelli, Ignacio | Waring, Thomas | Nair, Roshna V. | Sokleva, Vanesa | Dobre, Oana | Cameron, Angus | Gauthier, Nils | Lamaze, Christophe | Del Campo, Aránzazu | Starborg, Tobias | Zech, Tobias | Goetz, Jacky G. | Paluch, Ewa K. | Schwartz, Jean-Marc | Caswell, Patrick T.

Developmental Cell , 2019, 51 (4), 460-475.
http://www.sciencedirect.com/science/article/pii/S153458071930735X

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Differentiation of the human liver progenitor cell line (HepaRG) on a microfluidic-based biochip

Jang, Mi | Kleber, Astrid | Ruckelshausen, Thomas | Betzholz, Ralf | Manz, Andreas

Journal of Tissue Engineering and Regenerative Medicine , 2019, 13 (3), 482-494.
https://onlinelibrary.wiley.com/doi/abs/10.1002/term.2802

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Nanoscale Characteristics and Antimicrobial Properties of (SI-ATRP)-Seeded Polymer Brush Surfaces

Oh, Yoo Jin | Khan, Essak S. | del Campo, Aránzazu | Hinterdorfer, Peter | Li, Bin

ACS Applied Materials & Interfaces , 2019, 11 (32), 29312-29319.
https://doi.org/10.1021/acsami.9b09885

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