Dynamic Biomaterials

Prof. Dr. Aránzazu del Campo
Prof. Dr. Aránzazu del Campo
Head of Dynamic Biomaterials
Telefon: +49 (0)681-9300-510
E-mail: Aranzazu.DelCampo@leibniz-inm.de
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Contact

Dr. Aleeza Farrukh, INM – Leibniz-Institut für Neue Materialien gGmbH
Dr. Aleeza Farrukh
Stv. Leiterin Dynamische Biomaterialien
Phone: +49 (0)681-9300-315
E-mail: aleeza.farrukh@leibniz-inm.de
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Martina Bonnard
Secretary
Phone: +49 (0)681-9300-397
E-mail: martina.bonnard@leibniz-inm.de
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Team Members
B.Sc. Israa Abdulrahman Mohammed Kheir Elh
Phone: +49 (0)681-9300-351
E-mail: Israa.Abdulrahman@leibniz-inm.de
Daniel Ablahad
Phone: +49 (0)681-9300-181
E-mail: Daniel.Ablahad@leibniz-inm.de
Britta Abt
Phone: +49 (0)681-9300-363
E-mail: Britta.Abt@leibniz-inm.de
Dr.-Ing. Sener Albayrak
Phone: +49 (0)681-9300-157
E-mail: Sener.Albayrak@leibniz-inm.de
Dr. Gerardo Asensio Martín
Phone: +49 (0)681-9300-315
E-mail: gerardo.asensiomartin@leibniz-inm.de
Dipl.-Chem. Stefan Brück
Phone: +49 (0)681-9300-245
E-mail: stefan.brueck@leibniz-inm.de
B.Sc. Jesús Chong Talavera
Phone: +49 (0)681-9300-108/251
E-mail: jesus.chong@leibniz-inm.de
Semhar Eyob
Phone: +49 (0)681-9300-414
E-mail: semhar.eyob@leibniz-inm.de
M.Sc. Hafiz Syed Usama bin Farrukh
Phone: +49 (0)681-9300-360
E-mail: Usama.Farrukh@leibniz-inm.de
Dr. Aleeza Farrukh
Phone: +49 (0)681-9300-315
E-mail: aleeza.farrukh@leibniz-inm.de
ORCID: https://orcid.org/0000-0002-0711-0419
Dr. Jun Feng
Phone: +49 (0)681-9300-214
E-mail: jun.feng@leibniz-inm.de
M.Sc. Annalena Elisabeth Frank
E-mail: annalena.frank@leibniz-inm.de
B.Sc. Daniel Alfonso Garcia Sanchez
Phone: +49 (0)681-9300-245
E-mail: daniel.sanchez@leibniz-inm.de
Dr. Hannah Jahn-Kelleter
Phone: +49 (0)681-9300-384
E-mail: Hannah.Jahn-Kelleter@leibniz-inm.de
M.Sc. Zahra Kafrashian
Phone: +49 (0)681-9300-237
E-mail: zahra.kafrashian@leibniz-inm.de
ORCID: https://orcid.org/0000-0003-2960-7597
M.Sc. Hanuman Chowdary Kalari
Phone: +49 (0)681-9300-401
E-mail: Hanuman.Kalari@leibniz-inm.de
ORCID: https://orcid.org/0000-0002-2229-317X
Dr. Jennifer Yvonne Kasper
Phone: +49 (0)681-9300-345
E-mail: Jennifer.Kasper@leibniz-inm.de
M.Sc. Mokhamad Khamdan
Phone: +49 (0)681-9300-349
E-mail: mokhamad.khamdan@leibniz-inm.de
Dr. Steffen Krauser
Phone: +49 (0)681-9300-401
E-mail: steffen.krauser@leibniz-inm.de
Dr. Rinku Kumar
Phone: +49 (0)681-9300-316
E-mail: rinku.kumar@leibniz-inm.de
Prof. Dr. Juan Mancebo Aracil
Phone: +49 (0)681-9300-155
E-mail: juan.mancebo@leibniz-inm.de
M.Sc. Joëlle Aurelie Mekontso Ngaffo
Phone: +49 (0)681-9300-247
E-mail: joelle.mekontso@leibniz-inm.de
Dr. Christian Müller
Phone: +49 (0)681-9300-315
E-mail: christian.mueller@leibniz-inm.de
M.Sc. Ann-Cathrin Schlapp
Phone: +49 (0)681-9300-214
E-mail: Ann-Cathrin.Schlapp@leibniz-inm.de
Silke Siegrist
Phone: +49 (0)681-9300-363
E-mail: silke.siegrist@leibniz-inm.de
M.Sc. Therese Steudter
Phone: +49 (0)681-9300-384
E-mail: therese.steudter@leibniz-inm.de
M.Sc. Lara Luana Teruel Enrico
Phone: +49 (0)681-9300-282
E-mail: LaraLuana.TeruelEnrico@leibniz-inm.de
Lennart Weismantel
Phone: +49 (0)681-9300-152
E-mail: lennart.weismantel@leibniz-inm.de
Research

Hydrogels with latent properties

By integrating phototriggers and light-responsive molecular motors in polymeric networks, we develop 4D hydrogels with optoregulated (bio)chemical activity, crosslinking, degradation, or mechanoactuation. These are used for biophysical studies of cell response to changes in the biochemical and mechanical signals of the extracellular environment.

Model Cellular Microenvironments

We build synthetic models of cell-matrix and cell-cell interfaces with encoded biochemical, mechanical and dimensional signals. To accelerate discovery, we develop material microarrays for high-throughput biophysical experimentation and apply them to study multifactorial cell responses.

Living Therapeutic Devices

We develop bioinks and apply biofabrication technologies for functional and safe encapsulation of cells in medical devices. We focus on self-replenishable living therapeutic materials which integrate drug biofactories and have unlimited therapeutic release. We aim for innovation in ocular therapeutics with living, self-replenishable drug-eluting contact lenses.

Partner

Selected Publications

2021
Thiol-Methylsulfone-Based Hydrogels for Cell Encapsulation: Reactivity Optimization of Aryl-Methylsulfone Substrate for Fine-Tunable Gelation Rate and Improved Stability

Paez, Julieta I. | de Miguel-Jiménez, Adrián | Valbuena-Mendoza, Rocío | Rathore, Aditi | Jin, Minye | Gläser, Alisa | Pearson, Samuel | del Campo, Aránzazu

Biomacromolecules , 2021, 22 (7), 2874–2886.
https://doi.org/10.1021/acs.biomac.1c00256

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Lighting the Path: Light Delivery Strategies to Activate Photoresponsive Biomaterials In Vivo

Pearson, Samuel | Feng, Jun | del Campo, Aránzazu

Advanced Functional Materials , 2021, 31 (50), 2105989.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202105989

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Emerging Biofabrication Techniques: A Review on Natural Polymers for Biomedical Applications

Puertas-Bartolomé, María | Mora-Boza, Ana | García-Fernández, Luis

Polymers , 2021, 13 (8), 1209.
https://www.mdpi.com/2073-4360/13/8/1209

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Development of bioactive catechol functionalized nanoparticles applicable for 3D bioprinting

Puertas-Bartolomé, María | Włodarczyk-Biegun, Małgorzata K. | del Campo, Aránzazu | Vázquez-Lasa, Blanca | San Román, Julio

Materials Science and Engineering: C , 2021, 131 112515.
https://www.sciencedirect.com/science/article/pii/S092849312100655X

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Thiol-Methylsulfone-Based Hydrogels for Cell Encapsulation: Reactivity Optimization of Aryl-Methylsulfone Substrate for Fine-Tunable Gelation Rate and Improved Stability

Paez, Julieta I. | de Miguel-Jiménez, Adrián | Valbuena-Mendoza, Rocío | Rathore, Aditi | Jin, Minye | Gläser, Alisa | Pearson, Samuel | del Campo, Aránzazu

Biomacromolecules , 2021, 22 (7), 2874–2886.
https://doi.org/10.1021/acs.biomac.1c00256

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Targeting the Microtubule-Network Rescues CTL Killing Efficiency in Dense 3D Matrices

Zhao, Renping | Zhou, Xiangda | Khan, Essak S. | Alansary, Dalia | Friedmann, Kim S. | Yang, Wenjuan | Schwarz, Eva C. | del Campo, Aránzazu | Hoth, Markus | Qu, Bin

Frontiers in Immunology , 2021, 12 (3309), 729820.
https://www.frontiersin.org/article/10.3389/fimmu.2021.729820

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Targeting the Microtubule-network to improve CTL killing capacity in dense 3D matrices

Zhao, Renping | Zhou, Xiangda | Khan, Essak S. | Alansary, Dalia | Friedmann, Kim S. | Yng, Wenjuan | Schwarz, Eva C. | del Campo, Aránzazu | Hoth, Markus | Qu, Bin

European Journal of Immunology , 2021, 51 46.
https://onlinelibrary.wiley.com/doi/epdf/10.1002/eji.202170200

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2020
Anti-correlation of HER2 and focal adhesion complexes in the plasma membrane

Weinberg, Florian | Han, Mitchell Kim Liong | Dahmke, Indra Navina | Del Campo, Aránzazu | de Jonge, Niels

PLOS ONE , 2020, 15 (6), e0234430.
https://doi.org/10.1371/journal.pone.0234430

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Printed Soft Optical Waveguides of PLA Copolymers for Guiding Light into Tissue

Feng, Jun | Jiang, Qiyang | Rogin, Peter | Oliveira, Peter William de | del Campo, Aránzazu

ACS Applied Materials & Interfaces , 2020, 12 (18), 20287-20294.
https://doi.org/10.1021/acsami.0c03903

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Macroscopic self-evolution of dynamic hydrogels to create hollow interiors

Han, Lu | Zheng, Yijun | Luo, Hao | Feng, Jun | Engstler, Roxanne | Xue, Lulu | Jing, Guangyin | Deng, Xu | del Campo, Aránzazu | Cui, Jiaxi

Angewandte Chemie International Edition , 2020, 59 (14), 5611-5615.
https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201913574

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