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Team Members
Research
Hydrogels with latent properties
By integrating phototriggers and light-responsive molecular motors in polymeric networks, we develop 4D hydrogels with optoregulated (bio)chemical activity, crosslinking, degradation, or mechanoactuation. These are used for biophysical studies of cell response to changes in the biochemical and mechanical signals of the extracellular environment.
Model Cellular Microenvironments
We build synthetic models of cell-matrix and cell-cell interfaces with encoded biochemical, mechanical and dimensional signals. To accelerate discovery, we develop material microarrays for high-throughput biophysical experimentation and apply them to study multifactorial cell responses.
Living Therapeutic Devices
We develop bioinks and apply biofabrication technologies for functional and safe encapsulation of cells in medical devices. We focus on self-replenishable living therapeutic materials which integrate drug biofactories and have unlimited therapeutic release. We aim for innovation in ocular therapeutics with living, self-replenishable drug-eluting contact lenses.
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Selected Publications
Wlodarczyk-Biegun, Malgorzata | Zielinski, Piotr | Gladysz, Magdalena | Hofman, Anno | Wu, Xixi | Villiou, Maria | Koch, Marcus | del Campo, Aránzazu | Kamperman, Marleen
Tissue Engineering A , 2022, 28 (Suppl. 1), S362-S362.
https://www.liebertpub.com/doi/epdf/10.1089/ten.tea.2022.29025.abstracts
Włodarczyk-Biegun | Villiou, Maria | Koch, Klaus Peter | Muth, Christina | Wang | Ott | del Campo
ACS Biomaterials Science & Engineering , 2022, 8 (9), 3899-3911.
https://pubs.acs.org/doi/10.1021/acsbiomaterials.2c00623
Yang, Wenjuan | Denger, Andreas | Diener, Caroline | Küppers, Frederic | Soriano-Baguet, Leticia | Schäfer, Gertrud | Yanamandra, Archana K. | Zhao, Renping | Knörck, Arne | Schwarz, Eva C. | Hart, Martin | Lammert, Frank | Roma, Leticia Prates | Brenner, Dirk | Christidis, Grigorios | Helms, Volkhard | Meese, Eckart | Hoth, Markus | Qu, Bin
Frontiers in Immunology , 2022, 13 831680.
https://www.frontiersin.org/article/10.3389/fimmu.2022.831680
Alhayek, Alaa | Khan, Essak S. | Schönauer, Esther | Däinghaus, Tobias | Shafiei, Roya | Voos, Katrin | Han, Mitchell K. L | Ducho, Christian | Posselt, Gernot | Wessler, Silja | Brandstetter, Hans | Haupenthal, Jörg | del Campo, Aránzazu | Hirsch, Anna K. H.
Advanced Therapeutics , 2022, 5 (3), 2100222.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adtp.202100222
Feng, Jun | Zheng, Yijun | Jiang, Qiyang | Włodarczyk-Biegun, Małgorzata K. | Pearson, Samuel | del Campo, Aránzazu
Advanced Materials Technologies , 2022, 7 (10), 2101539.
https://onlinelibrary.wiley.com/doi/abs/10.1002/admt.202101539
Jin, Minye | Gläser, Alisa | Paez, Julieta I.
Polymer Chemistry , 2022, 13 (35), 5116-5126.
http://dx.doi.org/10.1039/D2PY00481J
Jin, Minye | Koçer, Gülistan | Paez, Julieta I.
ACS Applied Materials & Interfaces , 2022, 14 (4), 5017-5032.
https://doi.org/10.1021/acsami.1c22186
Koçer, Gülistan | Albino, Inês M. C. | Verheijden, Mark L. | Jonkheijm, Pascal
Bioorganic & Medicinal Chemistry , 2022, 68 116850.
https://www.sciencedirect.com/science/article/pii/S0968089622002425
Zhang, Jingnan | Zhao, Renping | Li, Bin | Farrukh, Aleeza | Hoth, Markus | Qu, Bin | del Campo, Aránzazu
Acta Biomaterialia , 2021, 119 234-246.
http://www.sciencedirect.com/science/article/pii/S1742706120306176
Zhao, Renping | Zhou, Xiangda | Khan, Essak S. | Alansary, Dalia | Friedmann, Kim S. | Yang, Wenjuan | Schwarz, Eva C. | del Campo, Aránzazu | Hoth, Markus | Qu, Bin
Frontiers in Immunology , 2021, 12 (3309), 729820.
https://www.frontiersin.org/article/10.3389/fimmu.2021.729820