Dynamic Biomaterials

Prof. Dr. Aránzazu del Campo
Prof. Dr. Aránzazu del Campo
Head of Dynamic Biomaterials
Telefon: +49 (0)681-9300-510
E-mail: Aranzazu.DelCampo@leibniz-inm.de
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Contact

Dr. Aleeza Farrukh, INM – Leibniz-Institut für Neue Materialien gGmbH
Dr. Aleeza Farrukh
Stv. Leiterin Dynamische Biomaterialien
Phone: +49 (0)681-9300-315
E-mail: aleeza.farrukh@leibniz-inm.de
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Martina Bonnard
Secretary
Phone: +49 (0)681-9300-397
E-mail: martina.bonnard@leibniz-inm.de
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Team Members
B.Sc. Israa Abdulrahman Mohammed Kheir Elh
Phone: +49 (0)681-9300-351
E-mail: Israa.Abdulrahman@leibniz-inm.de
Daniel Ablahad
Phone: +49 (0)681-9300-181
E-mail: Daniel.Ablahad@leibniz-inm.de
Britta Abt
Phone: +49 (0)681-9300-363
E-mail: Britta.Abt@leibniz-inm.de
Dr.-Ing. Sener Albayrak
Phone: +49 (0)681-9300-157
E-mail: Sener.Albayrak@leibniz-inm.de
Dr. Gerardo Asensio Martín
Phone: +49 (0)681-9300-315
E-mail: gerardo.asensiomartin@leibniz-inm.de
Dipl.-Chem. Stefan Brück
Phone: +49 (0)681-9300-245
E-mail: stefan.brueck@leibniz-inm.de
B.Sc. Jesús Chong Talavera
Phone: +49 (0)681-9300-108/251
E-mail: jesus.chong@leibniz-inm.de
Semhar Eyob
Phone: +49 (0)681-9300-414
E-mail: semhar.eyob@leibniz-inm.de
M.Sc. Hafiz Syed Usama bin Farrukh
Phone: +49 (0)681-9300-360
E-mail: Usama.Farrukh@leibniz-inm.de
Dr. Aleeza Farrukh
Phone: +49 (0)681-9300-315
E-mail: aleeza.farrukh@leibniz-inm.de
ORCID: https://orcid.org/0000-0002-0711-0419
Dr. Jun Feng
Phone: +49 (0)681-9300-214
E-mail: jun.feng@leibniz-inm.de
M.Sc. Annalena Elisabeth Frank
E-mail: annalena.frank@leibniz-inm.de
B.Sc. Daniel Alfonso Garcia Sanchez
Phone: +49 (0)681-9300-245
E-mail: daniel.sanchez@leibniz-inm.de
Dr. Hannah Jahn-Kelleter
Phone: +49 (0)681-9300-384
E-mail: Hannah.Jahn-Kelleter@leibniz-inm.de
M.Sc. Zahra Kafrashian
Phone: +49 (0)681-9300-237
E-mail: zahra.kafrashian@leibniz-inm.de
ORCID: https://orcid.org/0000-0003-2960-7597
M.Sc. Hanuman Chowdary Kalari
Phone: +49 (0)681-9300-401
E-mail: Hanuman.Kalari@leibniz-inm.de
ORCID: https://orcid.org/0000-0002-2229-317X
Dr. Jennifer Yvonne Kasper
Phone: +49 (0)681-9300-345
E-mail: Jennifer.Kasper@leibniz-inm.de
M.Sc. Mokhamad Khamdan
Phone: +49 (0)681-9300-349
E-mail: mokhamad.khamdan@leibniz-inm.de
Dr. Steffen Krauser
Phone: +49 (0)681-9300-401
E-mail: steffen.krauser@leibniz-inm.de
Dr. Rinku Kumar
Phone: +49 (0)681-9300-316
E-mail: rinku.kumar@leibniz-inm.de
Prof. Dr. Juan Mancebo Aracil
Phone: +49 (0)681-9300-155
E-mail: juan.mancebo@leibniz-inm.de
M.Sc. Joëlle Aurelie Mekontso Ngaffo
Phone: +49 (0)681-9300-247
E-mail: joelle.mekontso@leibniz-inm.de
Dr. Christian Müller
Phone: +49 (0)681-9300-315
E-mail: christian.mueller@leibniz-inm.de
M.Sc. Ann-Cathrin Schlapp
Phone: +49 (0)681-9300-214
E-mail: Ann-Cathrin.Schlapp@leibniz-inm.de
Silke Siegrist
Phone: +49 (0)681-9300-363
E-mail: silke.siegrist@leibniz-inm.de
M.Sc. Therese Steudter
Phone: +49 (0)681-9300-384
E-mail: therese.steudter@leibniz-inm.de
M.Sc. Lara Luana Teruel Enrico
Phone: +49 (0)681-9300-282
E-mail: LaraLuana.TeruelEnrico@leibniz-inm.de
Lennart Weismantel
Phone: +49 (0)681-9300-152
E-mail: lennart.weismantel@leibniz-inm.de
Research

Hydrogels with latent properties

By integrating phototriggers and light-responsive molecular motors in polymeric networks, we develop 4D hydrogels with optoregulated (bio)chemical activity, crosslinking, degradation, or mechanoactuation. These are used for biophysical studies of cell response to changes in the biochemical and mechanical signals of the extracellular environment.

Model Cellular Microenvironments

We build synthetic models of cell-matrix and cell-cell interfaces with encoded biochemical, mechanical and dimensional signals. To accelerate discovery, we develop material microarrays for high-throughput biophysical experimentation and apply them to study multifactorial cell responses.

Living Therapeutic Devices

We develop bioinks and apply biofabrication technologies for functional and safe encapsulation of cells in medical devices. We focus on self-replenishable living therapeutic materials which integrate drug biofactories and have unlimited therapeutic release. We aim for innovation in ocular therapeutics with living, self-replenishable drug-eluting contact lenses.

Partner

Selected Publications

2024
Actin-templated Structures: Nature’s Way to Hierarchical Surface Patterns (Gecko’s Setae as Case Study)

Kasper, Jennifer Y. | Laschke, Matthias W. | Koch, Marcus | Alibardi, Lorenzo | Magin, Thomas M. | Niessen, Carien M. | del Campo, Aránzazu

Advanced Science , 2024, 11 (10), 2303816.
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202303816

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Biofunctional Polyacrylamide Hydrogels using Tetrazole-Methylsulfone Comonomer for Thiol Conjugation

Farrukh, Hafiz Syed Usama Bin | Milos, Frano | Álvarez, Ana D. | Pearson, Samuel | del Campo, Aránzazu

Advanced Materials Interfaces , 2024, 11 (13), 2301024.
https://onlinelibrary.wiley.com/doi/full/10.1002/admi.202301024

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PIEZO1-mediated mechanosensing governs NK-cell killing efficiency and infiltration in three-dimensional matrices

Yanamandra, Archana K. | Zhang, Jingnan | Montalvo, Galia | Zhou, Xiangda | Diedenweg, Doreen | Zhao, Renping | Sharma, Shulagna | Hoth, Markus | Lautenschläger, Franziska | Otto, Oliver | del Campo, Aránzazu | Qu, Bin

European Journal of Immunology , 2024, 54 (3), e2350693.
https://onlinelibrary.wiley.com/doi/10.1002/eji.202350693

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Self-Lubricating, Living Contact Lenses

Puertas-Bartolomé, María | Gutierrez-Urrutia, Izabook | Teruel-Enrico, Lara Luana | Nguyen Duong, Cao | Desai, Krupansh K. | Trujillo, Sara | Wittmann, Christoph | del Campo, Aránzazu

Advanced Materials , 2024, 36 (27), 2313848.
https://onlinelibrary.wiley.com/doi/10.1002/adma.202313848

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Polyacrylamide Hydrogels as Versatile Biomimetic Platforms to Study Cell-Materials Interactions

Milos, Frano | Del Campo, Aránzazu

Advanced Materials Interfaces , 2024, 11 (34), 2400404.
https://onlinelibrary.wiley.com/doi/10.1002/admi.202400404

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2023
Encapsulation of bacteria in bilayer Pluronic thin film hydrogels: A safe format for engineered living materials

Bhusari, Shardul | Kim, Juhyun | Polizzi, Karen | Sankaran, Shrikrishnan | del Campo, Aránzazu

Biomaterials Advances , 2023, 145 213240.
https://www.sciencedirect.com/science/article/pii/S2772950822005179

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In vitro evaluation of immune responses to bacterial hydrogels for the development of living therapeutic materials

Yanamandra, Archana K. | Bhusari, Shardul | del Campo, Aránzazu | Sankaran, Shrikrishnan | Qu, Bin

Biomaterials Advances , 2023, 153 213554.
https://www.sciencedirect.com/science/article/abs/pii/S2772950823002777

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Gelation Kinetics and Mechanical Properties of Thiol-Tetrazole Methylsulfone Hydrogels Designed for Cell Encapsulation

Miguel-Jiménez, Adrián de | Ebeling, Bastian | Paez, Julieta I | Fink-Straube, Claudia | Pearson, Samuel | del Campo, Aránzazu

Macromolecular Bioscience , 2023, 23 (2), 2200419.
https://onlinelibrary.wiley.com/doi/abs/10.1002/mabi.202200419

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Engineered living materials for the conversion of a low-cost foodgrade precursor to a high-value flavonoid

Riedel, Florian | Puertas Bartolomé, María | Teruel Enrico, Lara Luana | Fink-Straube, Claudia | Nguyen Dong, Cao | Gherlone, Fabio | Huang, Ying | Valiante, Vito | del Campo, Aránzazu | Sankaran, Shrikrishnan

Frontiers in Bioengineering and Biotechnology , 2023, 11 1278062.
https://www.frontiersin.org/articles/10.3389/fbioe.2023.1278062/abstract

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Cytocompatibility evaluation of PEG-methylsulfone hydrogels

Trujillo, Sara | Kasper, Jennifer Y. | Miguel-Jimenez, Adrián De | Abt, Britta | Bauer, Alina | Mekontso Ngaffo, Joelle A. | Pearson, Samuel | del Campo, Aránzazu

ACS Omega , 2023, 8 (35), 32043-32052.
https://pubs.acs.org/doi/10.1021/acsomega.3c03952

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