Prof. Dr. Wilfried Weber,

Prof. Dr. Wilfried Weber

Scientific Director
Phone: +49 (0)681-9300-520

Curriculum Vitae

Since 2023      

Scientific Director of INM – Leibniz Institute for New Materials and Professor (W3) for New Materials at Saarland University, Saarbrücken, Germany


2019 – 2023      

Founding Scientific Director of the Cluster of Excellence CIBSS – Centre for Integrative Biological Signalling Studies


2009 – 2023     

Full Professor of Synthetic Biology, Faculty of Biology, University of Freiburg, Germany


2008 – 2009     

Group Leader, Department of Biosystems Science and Engineering, ETH Zurich, Switzerland


2008     

Co-founder of BioVersys GmbH, now BioVersys AG


2006 – 2008    

Group Leader, Institute for Chemical and Bioengineering, ETH Zurich


2003 – 2005  

Postdoc, Institute of Biotechnology, ETH Zurich


2003 – 2005  

Doctoral Studies, Institute of Biotechnology, ETH Zurich with Prof. Martin Fussenegger


2000 

Diplôme d’Ingénieur en Biotechnologie, Ecole Supérieure de Biotechnologie de Strasbourg, Strasbourg, France


Publications

2025
Signal-Amplifying Biohybrid Material Circuits for CRISPR/Cas-Based Single-Stranded RNA Detection

Mohsenin, Hasti | Schmachtenberg, Rosanne | Kemmer, Svenja | Wagner, Hanna J. | Johnston, Midori | Madlener, Sibylle | Dincer, Can | Timmer, Jens | Weber, Wilfried

Advanced Materials Technologies , 2025, 10 (2), 2400981.
https://onlinelibrary.wiley.com/doi/10.1002/admt.202400981

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Effects of formaldehyde on YAP and NF-κB signaling pathways in mammalian cells
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Engineered microbial living matter for diagnostics, prevention, and therapy
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Metabolite-Responsive Control of Transcription by Phase Separation-Based Synthetic Organelles

Jerez-Longres, Carolina | Weber, Wilfried

ACS Synthetic Biology , 2025, 14 (3), 711-718.
https://pubs.acs.org/doi/10.1021/acssynbio.4c00633

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Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice

Fischer, Alexandra A. M. | Robertson, Hanah B. | Kong, Deqiang | Grimm, Merlin M. | Grether, Jakob | Groth, Johanna | Baltes, Carsten | Fliegauf, Manfred | Lautenschlaeger, Franziska | Grimbacher, Bodo | Ye, Haifeng | Helms, Volkhard | Weber, Wilfried

Small , 2024 , 20 (38), 2311834.
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202311834

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2024
OptoREACT: Optogenetic Receptor Activation on Nonengineered Human T Cells

Armbruster, Anja | Ehret, Anna K. | Russ, Marissa | Idstein, Vincent | Klenzendorf, Melissa | Gaspar, Denise | Juraske, Claudia | Yousefi, O. Sascha | Schamel, Wolfang W. | Weber, Wilfried | Hörner, Maximilian

ACS Synthetic Biology , 2024, 13 (3), 752-762.
https://pubs.acs.org/doi/10.1021/acssynbio.3c00518

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An engineered surrogate poly(A) tail to wag translation initiation
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PenTag, a Versatile Platform for Synthesizing Protein-Polymer Biohybrid Materials

Mohsenin, Hasti | Pacheco, Jennifer | Kemmer, Svenja | Wagner, Hanna J. | Höfflin, Nico | Bergmann, Toquinha | Baumann, Tim | Jerez-Longres, Carolina | Ripp, Alexander | Jork, Nikolaus | Jessen, Henning J. | Fussenegger, Martin | Köhn, Maja | Timmer, Jens | Weber, Wilfried

Advanced Functional Materials , 2024, 34 (35), 2308269.
https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202308269

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Design of a Biohybrid Materials Circuit with Binary Decoder Functionality

Mohsenin, Hasti | Wagner, Hanna J. | Rosenblatt, Marcus | Kemmer, Svenja | Dreppe, Friedel | Huesgen, Pitter | Timmer, Jens | Weber, Wilfried

Advanced Materials , 2024, 36 (14), 2308092.
https://onlinelibrary.wiley.com/doi/full/10.1002/adma.202308092

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Lighting the way: recent developments and applications in molecular optogenetics
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