Electron Microscopy

The Electron Microscopy Core Facility is part of the Innovative Electron Microscopy Department. It ensures day-to-day operation of the electron microscopy facility and provides service to researchers at INM covering a large spectrum of electron microscopy techniques (from sample preparation to image analysis) on a broad variety of samples (from hard hybrid materials to soft hydrogels). The core facility team performs the experiments, assists researchers with their use of the facility equipment, provides training for users, and consults regarding best practices for electron microscopy sample preparation, imaging techniques and image processing.

The Service Group works in close cooperation with different research departments at INM, research groups of Saarland University and other institutions on the Campus. The Service Group is also involved in method development at the Innovative Electron Microscopy Department.

Head of Electron Microscopy

This position is currently vacant.
Please take a look at our job posting

Team Members
Analysis techniques

Analysis techniques offered by the Electron Microscopy Service group:

  • Scanning Electron Microscopy
  • Environmental Scanning Electron Microscopy
  • Focused Ion Beam microscopy and tomography
  • Conventional Transmission Electron Microscopy
  • Transmission Electron Microscopy at cryogenic temperatures
  • X-ray Energy Dispersive Spectroscopy
  • Electron Energy Loss Spectroscopy
  • Electron Backscatter Diffraction
Sample preparation techniques
  • Scanning Electron Microscopy
  • Environmental Scanning Electron Microscopy
  • Focused Ion Beam microscopy and tomography
  • Conventional Transmission Electron Microscopy
  • Transmission Electron Microscopy at cryogenic temperatures
  • X-ray Energy Dispersive Spectroscopy
  • Electron Energy Loss Spectroscopy
  • Electron Backscatter Diffraction

Publications

2019
Distribution of SiO2 nanoparticles in 3D liver microtissues

Fleddermann, Jana | Susewind, Julia | Peuschel, Henrike | Koch, Marcus | Tavernaro, Isabella | Kraegeloh, Annette

International Journal of Nanomedicine , 2019, 14 1411-1431.
https://doi.org/10.2147/IJN.S189888

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Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide

Hoppstädter, Jessica | Dembek, Anna | Linnenberger, Rebecca | Dahlem, Charlotte | Barghash, Ahmad | Fecher-Trost, Claudia | Fuhrmann, Gregor | Koch, Marcus | Kraegeloh, Annette | Huwer, Hanno | Kiemer, Alexandra K.

Frontiers in Immunology , 2019, 10 (1634), 1-17.
https://www.frontiersin.org/article/10.3389/fimmu.2019.01634

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Targeted T1 Magnetic Resonance Imaging Contrast Enhancement with Extraordinarily Small CoFe2O4 Nanoparticles

Piché, Dominique | Tavernaro, Isabella | Fleddermann, Jana | Lozano, Juan G. | Varambhia, Aakash | Maguire, Mahon L. | Koch, Marcus | Ukai, Tomofumi | Hernández Rodríguez, Armando J. | Jones, Lewys | Dillon, Frank | Reyes Molina, Israel | Mitzutani, Mai | González Dalmau, Evelio R. | Maekawa, Toru | Nellist, Peter D. | Kraegeloh, Annette | Grobert, Nicole

ACS Applied Materials & Interfaces , 2019, 11 (7), 6724-6740.
https://doi.org/10.1021/acsami.8b17162

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Sensors for biosensors: a novel tandem monitoring in a droplet towards efficient screening of robust design and optimal operating conditions

Semenova, Daria | Silina, Yuliya E. | Koch, Marcus | Micheli, Laura | Zubov, Alexandr | Gernaey, Krist V.

Analyst , 2019, 144 (8), 2511-2522.
http://dx.doi.org/10.1039/C8AN02261E

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Exploring the potential of high resolution inductively coupled plasma mass spectrometry towards non-destructive control and validation of electroless gold nanoparticles onto silicon nanowires hybrids

Silina, Yuliya E. | Koch, Marcus | Herbeck-Engel, Petra | Iatsunskyi, Igor

Analytical Methods , 2019, 11 3987-3995.
http://dx.doi.org/10.1039/C9AY01182J

Determination of the Surface Facets of Gold Nanorods in Wet-Coated Thin Films with Grazing-Incidence Wide Angle X-Ray Scattering

Zhang, Peng | Rothkirch, André | Koch, Marcus | Roth, Stephan | Kraus, Tobias

Particle & Particle Systems Characterization , 2019, 36 (12), 1900323_1-6.
https://onlinelibrary.wiley.com/doi/abs/10.1002/ppsc.201900323

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Evaluation of novel organosilane modifications of paper spray mass spectrometry substrates for analyzing polar compounds

Bambauer, Thomas P. | Maurer, Hans H. | Weber, Armin A. | Hannig, Matthias | Pütz, Norbert | Koch, Marcus | Manier, Sascha K. | Schneider, Marc | Meyer, Markus R.

Talanta , 2019, 204 677-684.
http://www.sciencedirect.com/science/article/pii/S0039914019305892

Combining Soft Polysilazanes with Melt-Shear Organization of Core–Shell Particles: On the Road to Polymer-Templated Porous Ceramics

Boehm, Anna K. | Ionescu, Emanuel | Koch, Marcus | Gallei, Markus

Molecules , 2019, 24 (19), 3553.
https://www.mdpi.com/1420-3049/24/19/3553

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The synergistic effect of chlorotoxin-mApoE in boosting drug-loaded liposomes across the BBB

Formicola, Beatrice | Dal Magro, Roberta | Montefusco-Pereira, Carlos V. | Lehr, Claus-Michael | Koch, Marcus | Russo, Laura | Grasso, Gianvito | Deriu, Marco A. | Danani, Andrea | Bourdoulous, Sandrine | Re, Francesca

Journal of Nanobiotechnology , 2019, 17 (1), 115_1-7.
https://doi.org/10.1186/s12951-019-0546-3

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Effect of fluoride mouthrinses and stannous ions on the erosion protective properties of the in situ pellicle

Kensche, A. | Buschbeck, E. | König, B. | Koch, Marcus | Kirsch, J. | Hannig, C. | Hannig, M.

Scientific Reports , 2019, 9 (1), 5336.
https://doi.org/10.1038/s41598-019-41736-7

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