Physical Analytics

The service group physical analytics covers electron optical and X-ray analytical investigations for all research departements of INM, research groups of the Saarland University of Saarland and external partners. For nanoscale microscopic investigations, transmission electron (TEM) and scanning electron microscopy (SEM) coupled with X-ray spectral analysis is used. TEM lamellae of a wide variety of samples are prepared inside with a focused ion beam (FIB) microscope and further thinned by focussed Argon ion beam (Nanomill) for atomic analytical analysis. Other preparation techniques such as microtomy, electrolytical polishing, ion milling with non-focusing ion beam and sputter coating are also available.

Aleeza-Farrukh, INM – Leibniz-Institut für Neue Materialien gGmbH
Dr. Marcus Koch
Head of Physical Analytics
Telefon: +49 (0)681-9300-144
Team Members
Phone: +49 (0)681-9300-135
Phone: +49 (0)681-9300-144
Phone: +49 (0)681-9300-247

Publications

2024
The RNA binding protein IGF2BP2/IMP2 alters the cargo of cancer cell-derived extracellular vesicles supporting tumor-associated macrophages

Mashayekhi, Vida | Schomisch, Annika | Rasheed, Sari | Aparicio-Puerta, Ernesto | Risch, Timo | Yildiz, Daniela | Koch, Marcus | Both, Simon | Ludwig, Nicole | Legroux, Thierry M. | Keller, Andreas | Müller, Rolf | Fuhrmann, Gregor | Hoppstädter, Jessica | Kiemer, Alexandra K.

2024, 22 344.
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01701-y

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A New Class of Polyion Complex Vesicles (PIC-somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms

Yildirim, Turgay | Bali, Aghiad | Koch, Marcus | Paul, Pascal | Latta, Lorenz | Scheider-Daum, Nicole | Gallei, Marcus | Lehr, Claus-Michael

Small , 2024, xxx (xxx), xxx.
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202401926

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Mechanistic aspects of glycerol oxidation on palladium electrocatalysts in model aqueous and fermentation media solutions

Silina, Yulia E. | Butyrskaya, E. V. | Koch, Marcus | Fink-Straube, Claudia | Korkmaz, Nuriye | Levchenko, M. G. | Zolotukhina, E. V.

Electrochimica Acta , 2024, 497 144479.
https://www.sciencedirect.com/science/article/pii/S0013468624007205?dgcid=rss_sd_all

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Melt electrowritten poly-lactic acid /nanodiamond scaffolds towards wound-healing patches

Wu, Xixi | Li, Wenjian | Herlah, Lara | Koch, Marcus | Wang, Hui | Schirhagl, Romana | Włodarczyk-Biegun

Materials Today Bio , 2024, 26 101112.
https://www.sciencedirect.com/science/article/pii/S2590006424001716

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Evaluation of the Transport and Binding of Dopamine-Loaded PLGA Nanoparticles for the Treatment of Parkinson’s Disease Using In Vitro Model Systems

Danz, Karin | Fleddermann, Jana | Koch, Marcus | Fecioru, Elena | Maahs, Lorenz | Kinsinger, Nicole | Krämer, Johannes | Kraegeloh, Annette | Wagner, Sylvia

2024, 16 (5), 571_1-15.
https://www.mdpi.com/journal/pharmaceutics

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Soft Synthetic Cells with Mobile Membrane Ligands for Ex Vivo Expansion of Therapy-Relevant T Cell Phenotypes

Burgstaller, Anna | Piernitzki, Nils | Küchler, Nadja | Koch, Marcus | Kister, Thomas | Eichler, Hermann | Kraus, Tobias | Schwarz, Eva C. | Dustin, Michael | Lautenschlaeger, Franziska | Staufer, Oskar

Small , 2024, xxx (xxx), xxx.
https://onlinelibrary.wiley.com/doi/10.1002/smll.202401844

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Towards controlled and simple design of non-enzymatic amperometric sensor for glycerol determination in yeast fermentation medium

Zolotukhina, Ekaterina V. | Butyrskaya, Elena | Fink-Straube, Claudia | Koch, Marcus | Silina, Yuliya E.

Analyticcal and bioanalytical chemistry , 2024, 416 3619-3630.
https://link.springer.com/article/10.1007/s00216-024-05316-7

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Biodegradable SPI-based hydrogel for controlled release of nanomedicines: A potential approach against brain tumors recurrence

Viale, Francesca | Ciprandi, Matilde | Leoni, Luca | Sierri, Giulia | Renda, Antonio | Barbugian, Federica | Koch, Marcus | Sesana, Silvia | Salvioni, Lucia | Colombo, Miriam | Mantegazza, Francesco | Russo, Laura | Re, Francesca

Journal of Drug Delivery Science and Technology , 2024, 96 105672.
https://www.sciencedirect.com/science/article/pii/S1773224724003411

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Targeting Intracellular Bacteria with Dual Drug-loaded Lactoferrin Nanoparticles

Andima, Moses | Boese, Annette | Paul, Pascal | Koch, Marcus | Loretz, Brigitta | Lehr, Claus-Michael

ACS Infectious Diseases , 2024, 10 (5), 1696–1710.
https://pubs.acs.org/doi/full/10.1021/acsinfecdis.4c00045

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Structure–Property Relationships of Granular Hybrid Hydrogels Formed through Polyelectrolyte Complexation

Es Sayed, Julien | Mukherjee, Adrivit | El Aani, Siham | Vengallur, Nayan | Koch, Marcus | Giuntoli, Andrea | Kamperman, Marleen

Macromolecules , 2024, 57 (7), 3190-3201.
https://doi.org/10.1021/acs.macromol.3c02335

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