Electron Microscopy

The Electron Microscopy Core Facility is part of the Innovative Electron Microscopy Department. It ensures day-to-day operation of the electron microscopy facility and provides service to researchers at INM covering a large spectrum of electron microscopy techniques (from sample preparation to image analysis) on a broad variety of samples (from hard hybrid materials to soft hydrogels). The core facility team performs the experiments, assists researchers with their use of the facility equipment, provides training for users, and consults regarding best practices for electron microscopy sample preparation, imaging techniques and image processing.

The Service Group works in close cooperation with different research departments at INM, research groups of Saarland University and other institutions on the Campus. The Service Group is also involved in method development at the Innovative Electron Microscopy Department.

Head of Electron Microscopy

This position is currently vacant.
Please take a look at our job posting

Team Members
Analysis techniques

Analysis techniques offered by the Electron Microscopy Service group:

  • Scanning Electron Microscopy
  • Environmental Scanning Electron Microscopy
  • Focused Ion Beam microscopy and tomography
  • Conventional Transmission Electron Microscopy
  • Transmission Electron Microscopy at cryogenic temperatures
  • X-ray Energy Dispersive Spectroscopy
  • Electron Energy Loss Spectroscopy
  • Electron Backscatter Diffraction
Sample preparation techniques
  • Scanning Electron Microscopy
  • Environmental Scanning Electron Microscopy
  • Focused Ion Beam microscopy and tomography
  • Conventional Transmission Electron Microscopy
  • Transmission Electron Microscopy at cryogenic temperatures
  • X-ray Energy Dispersive Spectroscopy
  • Electron Energy Loss Spectroscopy
  • Electron Backscatter Diffraction

Publications

2023
Chemical and Structural Comparison of Different Commercial Food Supplements for Silicon Uptake

Curto, Yannic | Koch, Marcus | Kickelbick, Guido

2023, 4 (1), 1-21.
https://www.mdpi.com/2673-6497/4/1/1

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Cell-Derived Vesicles for Antibiotic Delivery—Understanding the Challenges of a Biogenic Carrier System

Heinrich, Eilien | Hartwig, Olga | Walt, Christine | Kardani, Arefeh | Koch, Marcus | Pouralebi Jahromi, Leila | Hoppstädter, Jessica | Kiemer, Alexandra K. | Loretz, Brigitta | Lehr, Claus-Michael | Fuhrmann, Gregor

Small , 2023, 19 (25), 2207479.
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202207479

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Ageing-associated small RNA cargo of extracellular vesicles

Kern, Fabian | Kuhn, Thomas | Ludwig, Nicole | Simon, Martin | Gröger, Laura | Fabis, Natalie | Aparicio-Puerta, Ernesto | Salhab, Abdulrahman | Fehlmann, Tobias | Hahn, Oiver | Engel, Annika | Wagner, Viktoria | Koch, Marcus | Winek, Katarzyna | Soreq, Hermona | Nazarenko, Irina | Fuhrmann, Gregor | Wyss-Coray, Tony | Meese, Eckart | Keller, Verena | Laschke, Matthias W. | Keller, Andreas

RNA Biology , 2023, 20 (1), 482-494.
https://www.tandfonline.com/doi/full/10.1080/15476286.2023.2234713

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Testing of yeast cells damage using hydrogen peroxide spiking and Pd-NPs-based electrodes and impact of oxidoreductase presence on electrochemical read-out

Koch, Marcus | Katsen-Globa, A. | Zolotukhina, E. V. | Silina, Yulia E.

Biochemical Engineering Journal , 2023, 195 108908.
https://www.sciencedirect.com/science/article/abs/pii/S1369703X23001031

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Proteoid biodynamers for safe mRNA transfection via pH-responsive nanorods enabling endosomal escape

Lee, Sangeun | Nasr, Sarah | Rasheed, Sari | Liu, Yun | Hartwig, Olga | Kaya, Cansu | Boese, Annette | Koch, Marcus | Herrmann, Jennifer | Müller, Rolf | Loretz, Brigitta | Buhler, Eric | Hirsch, Anna K. H. | Lehr, Claus-Michael

Journal of Controlled Release , 2023, 353 915-929.
https://www.sciencedirect.com/science/article/pii/S0168365922008331

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2022
Melt Electrowriting enables fabrication of biommetic hierarchical scaffolds

Wlodarczyk-Biegun, Malgorzata | Zielinski, Piotr | Gladysz, Magdalena | Hofman, Anno | Wu, Xixi | Villiou, Maria | Koch, Marcus | del Campo, Aránzazu | Kamperman, Marleen

Tissue Engineering A , 2022, 28 (Suppl. 1), S362-S362.
https://www.liebertpub.com/doi/epdf/10.1089/ten.tea.2022.29025.abstracts

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Melt Electrowriting of Graded Porous Scaffolds to Mimic the Matrix Structure of the Human Trabecular Meshwork

Włodarczyk-Biegun | Villiou, Maria | Koch, Klaus Peter | Muth, Christina | Wang | Ott | del Campo

ACS Biomaterials Science & Engineering , 2022, 8 (9), 3899-3911.
https://pubs.acs.org/doi/10.1021/acsbiomaterials.2c00623

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The development of alginate-based amperometric nanoreactors for biochemical profiling of living yeast cells

Zolotukhina, E. V. | Katsen-Globa, A. | Koch, Marcus | Fink-Straube, Claudia | Sukmann, T. | Levchenko, M. G. | Silina, Yulia E.

Bioelectrochemistry , 2022, 145 108082.
https://www.sciencedirect.com/science/article/pii/S1567539422000330

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An Outer Membrane Vesicle-Based Permeation Assay (OMPA) for Assessing Bacterial Bioavailability

Richter, Robert | Kamal, Mohamed A. M. | Koch, Marcus | Niebuur, Bart-Jan | Huber, Anna-Lena | Goes, Adriely | Volz, Carsten | Vergalli, Julia | Kraus, Tobias | Müller, Rolf | Schneider-Daum, Nicole | Fuhrmann, Gregor | Pagès, Jean-Marie | Lehr, Claus-Michael

Advanced Healthcare Materials , 2022, 11 (5), 2101180.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.202101180

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Self-Assembly of Amphiphilic Carbosilane-Based Block Copolymers in Organic Media and Structure Formation in Colloidal Confinement

Hübner, Hanna | Niebuur, Bart-Jan | Büttner, Thomas | Koch, Marcus | Stühn, Bernd | Kraus, Tobias | Scheschkewitz, David | Gallei, Markus

Macromolecules , 2022, 55 (21), 9442-9451.
https://doi.org/10.1021/acs.macromol.2c01853

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