Publications

2024

H. S. U. Farrukh, F. Milos, A. Díaz Álvarez, S. Pearson, A. del Campo
Biofunctional polyacrylamide hydrogels using tetrazole-methylsulfone comonomer for thiol conjugation
Advanced Materials Interfaces, 2024, early view
doi:10.1002/admi.202301024

J. Y. Kasper, M. W. Laschke, M. Koch, L. Alibardi, T. Magin, C. M. Niessen, A. del Campo
Actin-templated Structures: Nature’s Way to Hierarchical Surface Patterns (Gecko’s Setae as Case Study)
Advanced Science, 2024, 11, (10), 2303816
doi:10.1002/advs.202303816

S. Bhusari, M. Hoffmann, P. Herbeck-Engel, S. Sankaran, M. Wilhelm, A. del Campo
Rheological behavior of Pluronic/Pluronic diacrylate hydrogel used for bacteria encapsulation in engineered living materials
Soft matter, 2024, 20, 1320-1332
doi:10.1039/D3SM01119D

2023

R. Florian, M. Puertas Bartolomé, L.L. Teruel Enrico, C. Fink-Straube, N. C. Dong, F. Gherlone, Y. Huang, V. Valiante, A. del Campo, S. Sankaran
Engineered living materials for the conversion of a low-cost foodgrade precurosor to a high-value flavonoid
Frontiers in Bioengineering and Biotechnology, 2023, 11, 1278062
doi:10.3389/fbioe.2023.1278062

S. Trujillo, J. Kasper, A. de Miguel-Jiménez, B. Abt, A. Bauer, J. Mekontso, s. Pearson, A. de. Campo
Cytocompatibility evaluation of PEG-methylsulfone hydrogels
ACS Omega, 2023, 8, 32043
doi:10.1021/acsomega.3c03952

A. K. Yanamandra, S. Bhusari, A. del Campo, S. Sankaran, B. Qu
In vitro evaluation of immune responses to bacterial hydrogels for the development of living therapeutic materials
Biomaterials Advances, 2023, 153, 213554
doi:10.1016/j.bioadv.2023.213554

A. Mora-Boza, S. Acosta, M. Puertas-Bartolomé
Biopolymers for the development of living materials for biomedical applications
Biopolymers / ed. V. Sessini.- Elsevier, 2023.- Chapter 9.- S. 263-294
doi:10.1016/B978-0-323-90939-6.00005-4

S. Bhusari, M. Hoffmann, P. Herbeck-Engel, S. Sankaran, M. Wilhelm, A. del Campo
Rheological behavior of Pluronic/Pluronic diacrylate hydrogels used for bacteria encapsulation in living materials
was published online as preprint
bioRxiv 2023
doi:10.1101/2023.03.29.534703

A. de Miguel-Miménez, B. Ebeling, J. I. Paez, C. Fink-Straube, S. Pearson, A. del Campo
Gelation kinetics and mechanical properties of thiol-tetrazolemethylsulfone hydrogels designed for cell encapsulation
Macromolecular Bioscience, 2023, 23, (2), 2200419
doi:10.1002/mabi.202200419

2022

A. de Miguel-Jiménez, B. Ebeling, J.I. Paez, C.Fink-Straube, S. Pearson, A. del Campo
Gelation kinetics of thiol-methylsulfone (MS) hydrogel formulations for 3D cell culture
was published online as preprint
chemRxiv 2022
doi: 10.26434/chemrxiv-2022-svh1x

S. Bhusari, J. Kim, K. Polizzi, S. Sankaran, A. del Campo
Encapsulation of bacteria in bilayer Ploronic thin film hydrogels: a safe format for engineered living materials
was published online as preprint
bioRxiv 2022
doi: 10.1101/2022.09.29.510162

A. Yanamandra, S. Bhusari,A. del Campo, S. Sankaran, B.Qu
In vitro evaluation of immune responses to bacterial hydrogels for the development of living therapeutic materials
was published online as preprint
bioRxiv 2022
doi: 10.1101/2022.09.16.508081

B. Li, A. Colak, J. Blass, M. Han, J. Zhang, Y. Zheng, Q. Jiang, R. Bennewitz, A. del Campo
Molecular stiffness cues of an interpenetrating network hydrogel for cell adhesion
Materials Today Bio, 2022, 15, 100323
doi:10.1016/j.mtbio.2022.100323

J. Feng, Y. Zheng, Q. Jiang, M. K. Włodarczyk-Biegun, S. Pearson, A. del Campo
Elastomeric optical waveguides by extrusion printing
Advanced materials technologies, 7, (10), 2101539
doi:10.1002/admt.202101539

A. Alhayek, E.S. Khan, E. Schönauer, T. Däinghaus, R. Shafiei, K. Voos, M.K.L. Han, C. Ducho, G. Posselt, S. Wessler, H. Brandstetter, J. Haupenthal, A. del Campo, A.K.H. Hirsch
Inhibiton of collagenase Q1 of Bacillus cereus as a Novel Antivirulence strategy for the treatment of skin-wound infections
Advanced Therapeutics 2022,5, (3), 2100222
doi:https://doi.org/10.1002/adtp.202100222

S. Bhusari, S. Sankaran, A. del Campo
Regulating bacterial behavior within hydrogels of tunable viscoelasticity
Advanced Science, 2022, 9, (17), 2106026
doi:10.1002/advs.202106026
was published online as preprint
bioRxiv 2022
doi:10.1101/2022.01.06.475183

2021

S. Pearson, J. Feng, A. del Campo
Lighting the Path: Light Delivery Strategies to Activate Photoresponsive Biomaterials In Vivo
Advanced Functional Materials, 2021, 31, (50), 2105989
doi:10.1002/adfm.202105989

A. Rodrigo-Navarro, S. Sankaran, J. Dalby, A. del Campo, M. Salmeron-Sanchez
Engineered Living Biomaterials
Nature Reviews Materials 2021, 6, 1175-1190
doi:10.1038/s41578-021-00350-8

M. Puertas-Bartolomé, M. K. Wlodarczyk-Biegun, A. de Campo, V. Vázquez-Lasa, J. San Román
Development of bioactive catechol functionalized nanoparticles applicable for 3D bioprinting
Materials Science & Engineering C 2021, 131, 112515
doi:10.1016/j.msec.2021.112515

R. Zhao, X. Zhou, E.S. Khan, D. Alansary, K.S. Friedmann, W. Yang, E.C. Schwarz, A. de. Campo, M. Hoth, B. Qu
Targeting the microtubule-network rescues CTL killing efficiency in dense 3D matrices
Frontiers in immunology 2021, 12, 729820
doi:10.3389/fimmu.2021.729820

R.V. Nair, A. Farrukh, A. del Campo
Light-regulated angiogenesis via a phototriggerable VEGF peptidomimetic
Advanced Healthcare Materials 2021,, 10 (14), 2100488
doi:10.1002/adhm.202100488

Highlight article
Y. Zheng, M.K.L. Han, R. Zhao, J. Blass, J. Zhang, D.W. Zhou, J.-R. Colard-Itté, D. Datler, M. Hoth, A.J. García, B. Qu, R. Bennewitz, N. Guiseppone, A. de Campo
Optoregulated force application to cellular receptors using molecular motors
Nature Communications 2021, 12, 3580
doi:https://doi.org/10.1038/s41467-021-23815-4
was published online as preprint
bioRxiv 2020
doi: 10.1101/2020.03.31.015198

J.-C. Escolano, A.V. Taubenberger, S. Abuhattum, C. Schweitzer, A. Farrukh, A. del Campo, Clare E. Bryant, J. Guck
Compliant substrates enhance macrophage cytokine release and NLRP3 inflammasome formation during their pro-inflammatory response
Frontiers in Cell and Developmental Biology 2021, 9, 639815
doi:10.3389/fcell.2021.639815

R. Zhao, X. Zhou, E.S. Khan, D. Alansary, K.S. Friedmann, W. Yang, E.C. Schwarz, A.del Campo, M.Hoth, B. Qu
Collagen density defines 3D migration of CTLs and their consequent cytotoxicity against tumor cells
was published online as preprint
BioRxiv 2021
doi: 10.1101/2021.03.16.435689

J.I. Paez, A. de Miguel-Jiménez, R. Valbuena-Mendoza, A. Rathore, M. Jin, A. Gläser, S. Pearson, A. del Campo
Thiol-methylsulfone-based hydrogels for cell encapsulation: reactivity optimization of aryl-methylsulfone substrate for fine-tunable gelation rate and improved stability
Biomacromolecules 2021, 22 (7), 2874–2886
doi:10.1021/acs.biomac.1c00256
was published online as preprint
ChemRxiv 2021
link: https://chemrxiv.org/articles/preprint/Thiol-methylsulfone-based_Hydrogels_for_Cell_Encapsulation_Reactivity_Optimization_of_Aryl-methylsulfone_Substrate_for_Fine-tunable_Gelation_Rate_and_Improved_Stability/14115404

2020

A.C. Dumitru, D. Mohammed, M. Maja, J. Yang, S. Verstraeten, A. del Campo, M.‐P. Mingeot‐Leclercq, D. Tyteca, D.Alsteens
Label‐Free Imaging of Cholesterol Assemblies Reveals Hidden Nanomechanics of Breast Cancer Cells
Advanced Science 2020, 7 (18),
doi: 10.1002/advs.202002643

J. Zhang, R. Zhao, B. Li, A. Farrukh, M. Hoth, Q. Bin Qu, A. del Campo
Micropatterned soft hydrogels to study the interplay of receptors and forces in T cell activation
Acta biomaterialia 2020, 119, 234-246
doi: 10.1016/j.actbio.2020.10.028

Y. Zheng, Z. Chen, Q. Jiang, J. Feng, S. Wu and A. del Campo
Near-infrared-light regulated angiogenesis in a 4D hydrogel
Nanoscale 2020, 25, 13654-13661
doi: 10.1039/D0NR02552F

J. Feng, Y. Zheng, S. Bhusari, M. Villiou, S Pearson, A. del Campo
Printed degradable optical waveguides for guiding light into tissue
Advanced functional materials 2020, 30 (45), 2004327
doi: 10.1002/adfm.202004327

M. Puertas-Bartolomé, M. K. Wlodarczyk-Biegun, A. del Campo, B. Vázquez-Lasa, J. San Román
3D Printing of a reactive hydrogel bio-ink using a static mixing tool
Polymer 2020, 12, 1986
doi: 10.3390/polym12091986

M. Villiou, J.I. Paez, A. del Campo
Photodegradable Hydrogels for Cell Encapsulation and Tissue Adhesion
ACS Applied materials & interfaces 2020, 12, 37862-37872
doi: 10.1021/acsami.0c08568

J. Feng, Q. Jiang, P. Rogin, P.W. de Oliveira, A. del Campo
Printed soft optical waveguides of PLA copolymers for guiding light into tissue
ACS Applied materials & interfaces 12 (2020) 20287-20294
doi: 10.1021/acsami.0c03903

F. Weinberg, M.K.L. Han, I.N. Dahmke, A. del Campo, N. de Jonge
Anti-correlation of HER2 and focal adhesion complexes in the plasma membrane
PLOS one 2020
doi:10.1371/journal.pone.0234430

M. K. Włodarczyk-Biegun, J. I. Paez, M. Villiou, J. Feng, A. del Campo
Printability study of metal ion crosslinked PEG-catechol based inks
Biofabrication, 2020, 12, (3), 035009
doi: 10.1088/1758-5090/ab673a
was published online as preprint:
bioRxiv 2019
doi:10.1101/599290v1

Y. Zheng, M.K.L. Han, R. Zhao, J. Blass, J. Zhang, D.W. Zhou, J.-R. Colard-Itté, D. Datler, M. Hoth, A.J. García, B. Qu, R. Bennewitz, N. Guiseppone, A. de Campo
Optoregulated force application to cellular receptors using molecular motors
bioRxiv 2020
doi: 10.1101/2020.03.31.015198

X. Wang, B. Yang, D. Tan, Q. Li, B. Song, Z-S Wu, A. del Campo, M. Kappl, Z. Wang, S. N. Gorb, S. Liu, L. Xue
Bioinspired footed soft robot with unidirectional all-terrain mobility
Materials today 35 (2020), 42-49
doi: 10.1016/j.mattod.2019.12.028

J.I. Paez, A. Farrukh, R. Valbuena Mendoza, M. K. Włodarczyk-Biegun, A. del Campo
Thiol-methylsulfone based hydrogels for 3D cell encapsulation
ACS Applied Materials & Interfaces 2020, 12, 7, 8062-8072
doi:10.1021/acsami.0c00709
was published online as preprint
ChemRxiv 2019
doi:10.26434/chemrixv.8971136.v1

A. Mora-Boza, M. K. Włodarczyk-Biegun, A. del Campo, B. Vazquez-Lasa, J. San Roman
Glycerylphytate as ionic crosslinker for 3D printing of multi-layered scaffolds with improved shape fidelity and biological features
Biomaterials Science 2020, 8, 506-5016
doi:10.1039/C9BM01271K

Y. Zheng, M. Kim Liong Han, Q. Jiang, B. Li, J. Feng, A. del Campo
4D hydrogel for dynamic cell culture with orthogonal, wavelength-dependent mechanical and biochemical cues
Materials Horizons 2020, 7, 111-116
doi: 10.1039/c9mh00665f

L. Han, Y. Zheng, H. Luo, J. Feng, R. Engstler, L. Xue, G. Jing, X. Deng, A. del Campo, J. Cui
Macroscopic self‐evolution of dynamic hydrogels to create hollow interiors
Angewandte Chemie Int. Ed. 2020, 59, 4, 5611-5615
doi: 10.1002/anie.201913574

2019

J. H. R. Hetmanski, H. de Belly, R.V. Nair, V. Sokleva, O. Dobre, A. Cameron, N. Gauthier, C. Lamaze, J. Swift, A. del Campo, E. Paluch, J.-M. Schwartz, P. Caswell
Membrane Tension Orchestrates Rear Retraction in Matrix Directed Cell Migration
Developmental Cell, 2019, 51, (4), S. 460-475
doi:10.2139/ssrn.3249468

A. Çolak, B. Li, J. Blass, K. Koynov,A. del Campo and R.Bennewitz
The mechanics of single cross-links which mediate cell attachment at a hydrogel surface
Nanoscale, 2019, 11, S.11596-11604
doi:10.1039/C9NR01784D

C.A. Custódio, A. del Campo, R.L. Reis, J.F. Mano
Smart instructive polymer substrates for tissue engineering
Smart polymers and their applications.- 2nd. ed.- Elsevier, 2019.- S. 411-438
doi: 10.1016/B978-0-08-102416-4.00012-0

B. Li, M. Kappl, L. Han, J. Cui, F. Zhou, A. del Campo
Goosebumps-inspired microgel patterns with switchable adhesion and friction
Small 2019, 15, (35), 1902376
doi: 10.1002/smll.201902376

S. Sankaran, J. Becker, C. Wittmann, A. del Campo
Optoregulated Drug Release from an Engineered Living Material: Self‐Replenishing Drug Depots for Long‐Term, Light‐Regulated Delivery
Small 2019, 15, (5), 1804717
doi:10.1002/smll.201804717

A. Farrukh, J. I. Paez, A. del Campo
4D Biomaterials for Light‐Guided Angiogenesis
Advanced functional materials 2019, 29, (6), 1807734
doi:10.1002/adfm.201807734

S. Sankaran, A. del Campo
Optoregulated Protein Release from an Engineered Living Material
Advanced biosystems 2019, 3, (2), 1800312
doi:10.1002/adbi.201800312

2018

A. Farrukh, S. Zhao, A. del Campo
Microenvironments designed to support growth and function of neuronal cells
Frontiers in materials 2018, 5, (62), article 62
doi: 10.3389/fmats.2018.00062

Y. Zheng, A. Farrukh, A. del Campo
Optoregulated biointerfaces to trigger cellular responses
Langmuir 2018, 34, (48), 14459-14471
doi:10.1021/acs.langmuir.8b02634

S. Zhao, W. Fan, X. Guo, L. Xue, B. Berninger, M. J. Salierno and A. del Campo
Microenvironments to study migration and somal translocation in cortical neurons
Biomaterials 2018, 156, 238-247
doi:10.1016/j.biomaterials.2017.11.042

S. Sankaran, S. Zhao, C. Muth, J. Paez and A. del Campo
Toward Light-Regulated Living Biomaterials
Adv Sci 2018, 5, (8), 1800383
doi:10.1002/advs.201800383
ChemRxiv 2018
doi:10.26434/chemrxiv.5926381.v1

C. M. Rohles, L. Gläser, M. Kohlstedt, G. Gießelmann, S. Pearson, A. del Campo, J. Becker and C. Wittmann
A bio-based route to the carbon-5 chemical glutaric acid and to bionylon-6,5 using metabolically engineered Corynebacterium glutamicum
Green Chem 2018, 20, (20), 4662-4674
doi:10.1039/c8gc01901k

R. V. Nair, A. Farrukh and A. del Campo
A Photoactivatable α5β1-Specific Integrin Ligand
ChemBioChem 2018, 19, (12), 1280-1287
doi:10.1002/cbic.201800180
ChemRxiv 2018
doi:10.26434/chemrxiv.6097688.v1

E. Latorre, S. Kale, L. Casares, M. Gómez-González, M. Uroz, L. Valon, R. V. Nair, E. Garreta, N. Montserrat, A. del Campo, B. Ladoux, M. Arroyo and X. Trepat
Active superelasticity in three-dimensional epithelia of controlled shape
Nature 2018, 563, (7730), 203-208
doi:10.1038/s41586-018-0671-4

A. Farrukh, S. Zhao, J. I. Paez, A. Kavyanifar, M. Salierno, A. Cavalié and A. del Campo
In Situ, Light-Guided Axon Growth on Biomaterials via Photoactivatable Laminin Peptidomimetic IK(HANBP)VAV
ACS Appl Mater Interfaces 2018, 10, (48), 41129-41137
doi:10.1021/acsami.8b15517

A. Farrukh, W. Fan, S. Zhao, M. Salierno, J. I. Paez and A. Del Campo
Photoactivatable Adhesive Ligands for Light-Guided Neuronal Growth
ChemBioChem 2018, 19, (12), 1271-1279
doi:10.1002/cbic.201800118

2017

L. Xue, B. Sanz, A. Luo, K. T. Turner, X. Wang, D. Tan, R. Zhang, H. Du, M. Steinhart, C. Mijangos, M. Guttmann, M. Kappl and A. del Campo
Hybrid Surface Patterns Mimicking the Design of the Adhesive Toe Pad of Tree Frog
ACS Nano 2017, 11, (10), 9711-9719
doi:10.1021/acsnano.7b04994

M. K. Włodarczyk-Biegun and A. del Campo
3D bioprinting of structural proteins
Biomaterials 2017, 134, 180-201
doi:10.1016/j.biomaterials.2017.04.019

M. Iacomino, J. I. Paez, R. Avolio, A. Carpentieri, L. Panzella, G. Falco, E. Pizzo, M. E. Errico, A. Napolitano, A. del Campo and M. d’Ischia
Multifunctional Thin Films and Coatings from Caffeic Acid and a Cross-Linking Diamine
Langmuir 2017, 33, (9), 2096-2102
doi:10.1021/acs.langmuir.6b04079

J. Feng, X.-A. Ton, S. Zhao, J. Paez and A. del Campo
Mechanically Reinforced Catechol-Containing Hydrogels with Improved Tissue Gluing Performance
Biomimetics 2017, 2, (4), 23
doi: 10.339/biomimetics2040023

A. Farrukh, J. I. Paez, M. Salierno, W. Fan, B. Berninger and A. del Campo
Bifunctional Poly(acrylamide) Hydrogels through Orthogonal Coupling Chemistries
Biomacromolecules 2017, 18, (3), 906-913
doi:10.1021/acs.biomac.6b01784

A. Farrukh, F. Ortega, W. Fan, N. Marichal, J. I. Paez, B. Berninger, A. del Campo and M. J. Salierno
Bifunctional Hydrogels Containing the Laminin Motif IKVAV Promote Neurogenesis
Stem Cell Reports 2017, 9, (5), 1432-1440
doi:10.1016/j.stemcr.2017.09.002

2016

L. Xue, J. T. Pham, J. Iturri and A. del Campo
Stick-slip friction of PDMS surfaces for bioinspired adhesives
Langmuir 2016, 32, (10), 2428-2435
doi:10.1021/acs.langmuir.6b00513

M. J. Salierno, L. García-Fernandez, N. Carabelos, K. Kiefer, A. J. García and A. del Campo
Phototriggered fibril-like environments arbitrate cell escapes and migration from endothelial monolayers
Biomaterials 2016, 82, 113-123
doi:10.1016/j.biomaterials.2015.12.001

J. T. Pham, L. Xue, A. del Campo and M. Salierno
Guiding cell migration with microscale stiffness patterns and undulated surfaces
Acta Biomater 2016, 38, 106-115
doi:10.1016/j.actbio.2016.04.031

J. W. Neubauer, L. Xue, J. Erath, D. M. Drotlef, A. del Campo and A. Fery
Monitoring the contact stress distribution of gecko-inspired adhesives using mechano-sensitive surface coatings
ACS Appl Mater Inter 2016, 8, (28), 17870-17877
doi:10.1021/acsami.6b05327

A. Farrukh, J. I. Paez, M. Salierno and A. del Campo
Bioconjugating thiols to poly(acrylamide) gels for cell culture using methylsulfonyl co-monomers
Angew Chem Int Edit 2016, 55, (6), 2092-2096
doi:10.1002/anie.201509986

2015

J. I. Paez, O. Ustahüseyin, C. Serrano, X.-A. Ton, Z. Shafiq, G. K. Auernhammer, M. d’Ischia and A. del Campo
Gauging and tuning cross-linking kinetics of catechol-PEG adhesives via catecholamine functionalization
Biomacromolecules 2015, 16, (12), 3811-3818
doi:10.1021/acs.biomac.5b01126